Practice Exam Question Flashcards

1
Q

The expected frequency of an inherited gene combination is 35%. Population testing reveals that the observed frequency of the same gene combination is 55%. This is an example of:

A

Linkage disequilibrium

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

An individual is born lacking the GYB protein. Which phenotype would you expect to see as a result of this deletion?

A

S-s-U-; M,N will be unaffected

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What antigen is lacking in the McLeod Phenotype?

A

Kx

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What are some indirect costs of laboratory operation?

costs not directly related to a particular test

A
Staff Benefits
Service contracts
IT
Indirect labor (mangers) 
Overhead
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Irradiating of donor blood is intended to prevent which type of adverse transfusion reaction?

A

Transfusion associated Grat vs Host Disease (TA_GVHD)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

A donor who experiences tingling while donating apheresis platelets is most likely experiencing:

A

Calcium depletion from the anticoagulant

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Which of the following is proper procedure for preparation of platelet concentrates?

A

One light spin followed by one hard spin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

An Xg(a+) woman who marries an Xg(a-) man can bear:

A

Xg(a-) daughters
Xg(a+) daughters
Xg(a+) sons

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Which represents the genes and substances present in saliva, for an individual who is Group A, Le(a+b-)?

A

Genes: A, H, Le, sese
Saliva: contains Lea substance

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What ABORh is given for intrauterine transfusions?

A

O Negative is always given for exchange transfusion, since we don’t know the ABO and Rh type of the fetus.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

How much Factor VIII and fibrinogen will one unit of whole blood will typically yield?

A

80 IU of Factor VIII and 150 mg of fibrinogen

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

The use of EDTA plasma prevents activation of the classical complement pathway by:

A

Chelating Ca ions which prevents assembly of C1

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Most deaths from acute hemolytic transfusion reactions occur because of errors in:

A

Clerical Errors

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Which phenotypes will react with an Anti-f?

A

r, R0

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Hemosiderosis is an unfavorable effect of long term transfusion therapy. What drug is administered to remove excess iron from the body?

A

Deferoxamine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What reagents are commonly used to differentiate IgG from IgM antibodies

A

2-ME and DTT.

These reagents break down the disulfide bonds found in IgM antibodies, and denature them.