Practice Exam Question Flashcards
The expected frequency of an inherited gene combination is 35%. Population testing reveals that the observed frequency of the same gene combination is 55%. This is an example of:
Linkage disequilibrium
An individual is born lacking the GYB protein. Which phenotype would you expect to see as a result of this deletion?
S-s-U-; M,N will be unaffected
What antigen is lacking in the McLeod Phenotype?
Kx
What are some indirect costs of laboratory operation?
costs not directly related to a particular test
Staff Benefits Service contracts IT Indirect labor (mangers) Overhead
Irradiating of donor blood is intended to prevent which type of adverse transfusion reaction?
Transfusion associated Grat vs Host Disease (TA_GVHD)
A donor who experiences tingling while donating apheresis platelets is most likely experiencing:
Calcium depletion from the anticoagulant
Which of the following is proper procedure for preparation of platelet concentrates?
One light spin followed by one hard spin
An Xg(a+) woman who marries an Xg(a-) man can bear:
Xg(a-) daughters
Xg(a+) daughters
Xg(a+) sons
Which represents the genes and substances present in saliva, for an individual who is Group A, Le(a+b-)?
Genes: A, H, Le, sese
Saliva: contains Lea substance
What ABORh is given for intrauterine transfusions?
O Negative is always given for exchange transfusion, since we don’t know the ABO and Rh type of the fetus.
How much Factor VIII and fibrinogen will one unit of whole blood will typically yield?
80 IU of Factor VIII and 150 mg of fibrinogen
The use of EDTA plasma prevents activation of the classical complement pathway by:
Chelating Ca ions which prevents assembly of C1
Most deaths from acute hemolytic transfusion reactions occur because of errors in:
Clerical Errors
Which phenotypes will react with an Anti-f?
r, R0
Hemosiderosis is an unfavorable effect of long term transfusion therapy. What drug is administered to remove excess iron from the body?
Deferoxamine