Practice Exam 2

Question 1

The abbreviation “APUTTGAR” describes common steps in all viral infections. Which of the following is NOT one of these common steps:

a) uncoating
b) transformation
c) attachment
d) assembly
e) release

Answer 1

b) transformation

Question 2

Coronavirus (+)ssRNA is translated into a polyprotein that is then processed by:

a) proteases
b) mRNA splicing factors
c) ribosomes
d) RdRp
e) DdDp

Answer 2

a) proteases

Question 3

A virus with a DNA-dependent RNA polymerase (DdRp)…?

a) synthesizes DNA from an RNA template
b) synthesizes RNA from an DNA template
c) synthesizes DNA from a DNA template
d) synthesizes RNA from an RNA template

Answer 3

b) synthesizes RNA from an DNA template

Question 4

Bacterial restriction endonuclease enzymes target incoming viral ________ for cleavage.

a) (-)ssRNA
b) dsDNA
c) (+)ssRNA
d) ssDNA
e) dsRNA

Answer 4

b) dsDNA

Question 5

Coronavirus (+)ssRNA is translated in the host cell cytoplasm by:

a) mRNA splicing factors
b) DdDp
c) ribosomes
d) RdDp
e) proteases

Answer 5

c) ribosomes

Question 6

A virus is an obligate intracellular _______?

Answer 6

parasite??

Question 7

UV irradiation can inactivate a herpesvirus by damaging its dsDNA genome.

a) True
b) False

Answer 7

a) True

Question 8

Viruses with icosahedral capsids can infect diverse hosts including animals, insects, bacteria and plants.

a) True
b) False

Answer 8

a) True

Question 9

Some viruses are covered with host cell-derived lipids. This is known as an _________?

Answer 9

envelope

Question 10

Virus envelopes are typically studded with ___________ that play roles in viral attachment and entry into host cells.

a) matrix proteins
b) nucleocapsids
c) glycoproteins
d) polymerases

Answer 10

c) glycoproteins

Question 11

SARS-CoV-2 is an enveloped virus.

a) True
b) False

Answer 11

a) True

Question 12

SARS-CoV-2 has a single-stranded RNA genome.

a) True
b) False

Answer 12

a) True

Question 13

Influenza virus ____________ protein promotes attachment to host cells by binding to cell surface sialic acid sugars.

a) neuraminidase (NA)
b) NS1
c) matrix
d) hemagglutinin (HA)

Answer 13

d) hemagglutinin (HA)

Question 14

____________ describes the process whereby VAPs bind to host cell surface receptors to initiate the entry process.

Answer 14

Attachment

Question 15

___________ describes the process whereby a virus crosses host cell membranes and gains access to the cytoplasm.

Answer 15

Penetration

Question 16

__________ describes the process of decoding mRNAs to create proteins.

Answer 16

translation

Question 17

Virus receptors are proteins that have no other role in cell biology.

a) True
b) False

Answer 17

b) False