ppt5-antibiotiques et relation hote-microorganisme Flashcards

1
Q

antibiotique

A

petit composé fait par un microorganisme qui est bactériostatique ou bactéricide

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2
Q

histoire-ehrlich

A

rouge trypan affecte trypanosome responsable de la maladie du sommeil
arsphenamine contre spirochete qui cause syphilis

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3
Q

histoire-domagk

A

rouge prontosil tue streptocoques et staphylocoques pathogenes

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4
Q

histoire-fleming

A

penicilline

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5
Q

histoire-waksman

A

découvre streptomycine

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6
Q

toxicité sélective

A

toxique juste pour le pathogène sans endommager l’hote

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7
Q

dose thérapeutique

A

qté requise pour un traitement efficace sans tuer l’hote

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8
Q

dose toxique

A

tue l’hote

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9
Q

spectre d’activité

A

-étroit: actif contre nombre restreint
-large: actif contre plusieurs espèces microbiennes

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10
Q

provenance de l’antibiotique

A

naturel
purement synthétique
semi synthétique

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11
Q

mesurer l’activité anti microbienne

A

CMI: concentration minimale inhibitrice
CML: concentration minimale létale
-determiné par dilution en milieu liquide

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