PPT 4 Flashcards
Salbutamol
B2 agonist
Terbutaline
A selective beta-2 adrenergic agonist used as a bronchodilator
Salmeterol
Long-acting beta-2 adrenergic receptor agonist drug that is currently prescribed for the treatment of asthma and chronic obstructive pulmonary disease COPD
Formoterol
Long-acting beta-2 adrenergic receptor agonist drug that is currently prescribed for the treatment of asthma and chronic obstructive pulmonary disease COPD
Ipratropium
Antagonist of the muscarinic acetylcholine receptor
Tiotropium
Long-acting, antimuscarinic bronchodilator used in the management of chronic obstructive pulmonary disease (COPD) and asthma. Tiotropium acts mainly on M3 muscarinic receptors located in the airways to produce smooth muscle relaxation and bronchodilation
Glycopyrronium
Muscarinic competitive antagonist used as an antispasmodic, in some disorders of the gastrointestinal tract, and to reduce salivation with some anesthetics
Aclidinium
Aclidinium is a long-acting, competitive, and reversible anticholinergic drug that is specific for the acetylcholine muscarinic receptors. It binds to all 5 muscarinic receptor subtypes to a similar affinity. Aclidinium’s effects on the airways are mediated through the M3 receptor at the smooth muscle to cause bronchodilation
Beclometasone
Inhaled corticosteroid
One of the three drugs in the trimbow inhaler used for COPD
Aminophylline
Bronchodilator
Reduces airway responsiveness to histamine, methacholine, adenosine, and allergen
Competitively inhibits type III and type IV phosphodiesterase (PDE), the enzyme responsible for breaking down cyclic AMP in smooth muscle cells, possibly resulting in bronchodilation
Modified release theophylline
Same as aminophylline but modification of the drug allows for longer action
Fluticasone
Inhaled corticosteroid
Reduces inflammation in asthma patients
Hydrocortisone
Glucocorticoid
Used for acute asthma (as an adjunct)
Prednisolone
Steroid
Given for 5 days in COPD exacerbation
Sodium cromoglicate
Preventer for asthma
Stabilises mast cell membranes so histamine is not released