PPT 4 Flashcards

1
Q

Salbutamol

A

B2 agonist

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Terbutaline

A

A selective beta-2 adrenergic agonist used as a bronchodilator

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Salmeterol

A

Long-acting beta-2 adrenergic receptor agonist drug that is currently prescribed for the treatment of asthma and chronic obstructive pulmonary disease COPD

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Formoterol

A

Long-acting beta-2 adrenergic receptor agonist drug that is currently prescribed for the treatment of asthma and chronic obstructive pulmonary disease COPD

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Ipratropium

A

Antagonist of the muscarinic acetylcholine receptor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Tiotropium

A

Long-acting, antimuscarinic bronchodilator used in the management of chronic obstructive pulmonary disease (COPD) and asthma. Tiotropium acts mainly on M3 muscarinic receptors located in the airways to produce smooth muscle relaxation and bronchodilation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Glycopyrronium

A

Muscarinic competitive antagonist used as an antispasmodic, in some disorders of the gastrointestinal tract, and to reduce salivation with some anesthetics

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Aclidinium

A

Aclidinium is a long-acting, competitive, and reversible anticholinergic drug that is specific for the acetylcholine muscarinic receptors. It binds to all 5 muscarinic receptor subtypes to a similar affinity. Aclidinium’s effects on the airways are mediated through the M3 receptor at the smooth muscle to cause bronchodilation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Beclometasone

A

Inhaled corticosteroid

One of the three drugs in the trimbow inhaler used for COPD

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Aminophylline

A

Bronchodilator

Reduces airway responsiveness to histamine, methacholine, adenosine, and allergen

Competitively inhibits type III and type IV phosphodiesterase (PDE), the enzyme responsible for breaking down cyclic AMP in smooth muscle cells, possibly resulting in bronchodilation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Modified release theophylline

A

Same as aminophylline but modification of the drug allows for longer action

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Fluticasone

A

Inhaled corticosteroid

Reduces inflammation in asthma patients

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Hydrocortisone

A

Glucocorticoid

Used for acute asthma (as an adjunct)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Prednisolone

A

Steroid

Given for 5 days in COPD exacerbation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Sodium cromoglicate

A

Preventer for asthma

Stabilises mast cell membranes so histamine is not released

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Montelukast

A

Works by blocking the action of leukotriene D4 in the lungs resulting in decreased inflammation and relaxation of smooth muscl

17
Q

Zafirlukast

A

Leukotriene inhibitor

Leukotrienes promote inflammation and bronchoconstriction