ppt 1 Flashcards

1
Q

what is rad bio

A

describing and explaining the changes that radiation produces in biological cells and organisms

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2
Q

ionizing radiation such as x rays may produce harmful effects on living organisms such as…

A

-gross or microscopic
-lethal or non-lethal
-immediate or delayed

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3
Q

agricultural use of radiation…

A

-sterilize male pest insects and release them into wild population to decrease population growth
-irradiate grains, spices, fruits, milk etc to preserve foods and increase their shelf life

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4
Q

industrial use of radiation

A

-scientific research
-electrical power generation
-instrument and guages to measure thickness and density of material

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5
Q

medical use of radiation…

A

-sterilization of medical equipment
-use of xray for dx
-use of radioisotopes for dx
-use of xrays and gamma rays for treating cx
-use of Ab-radioisotope conjugates for treating cx (radioimmunotherapy)

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6
Q

what is ionizing radiation

A

-ion charged particles
-ionization= separation of orbital electrons from an atom
-ionizing radiation= enough energy to ionize the matter through which it passes
-mechanism in which human tissue is damaged

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7
Q

what happens when an ion sharing electrons by 2 atoms forms a molecular bond…

A

that bond is broken and thus the molecule falls apart

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8
Q

activity is

A

measure of how much radioactivity a radioactive material emits, measured in disintegrations/sec

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9
Q

measurements of activity

A

curies, becquerel

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10
Q

1 Ci=

A

3.7 x 10^10 disintegrations/sec

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11
Q

1 Becquerel=

A

1 disintegreations/sec

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12
Q

1 Ci=

A

3.7 x 10^10 Bq

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13
Q

exposure is…

A

measure of how many ion pairs are formed in a given volume of air when exposed to radiation.

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14
Q

what is exposure not

A

NOT meausre of energy absorbed or dose. NOT relate to amount of biological affetcs on human body

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15
Q

roentgen is the

A

amount of gamma or xrays which produce ions carrying one electrostatic unit of hcarge in one cm3 of dry air (usually expressed in R/min or R/hr

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16
Q

radiation absorbed dose (rad) is a

A

unit of meausring absorbed dose in any material (energy being depositied by radiation)
-applies to all radiation

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17
Q

radiation absorbed dose )rad) does not

A

-not take into acount potential effects of diff types of rad on body
-not measure of risk to body

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18
Q

equivalent dose measures

A

dose in a person in remr

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19
Q

rem stands for

A

roentgen equivalent man

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20
Q

what does rem take into account

A
  • energy absorbed dose
  • relative biological effects on the body due to diferent types of radiation
    -measure damage to human
21
Q

absorbed dose x quality factor

A

quality factor for xray and gamma and beta= 1
quality factor for aplha particles= 20

22
Q

what is occupational rad exposure recorded in

23
Q

dose rate is

A

how fast you reviece the dose (mrem/hr)

24
Q

dose is

A

amount of radiation you recieve (mrem)

25
linear no threshold approach says
no amount of radiation is absent of risk and as exp incr so does risk
26
what percent of fatality from cx
25%
27
what percent of fatality for informed exposue
0-1%
28
4 responses to radiation exposure CELLS
-undamaged -cell damaged but able to repair the damage and operate noramlly (only if minimally damaged) -cells damaged and repar but function abnormally -cells die
29
less sensitive cells do what upon rad exposure
slowly dividing cells that are more specialized (nerve cells)
30
more sensitive cells do what
cells divide more rapidly and non specificed (hemopoeitic cells)
31
acute radiation syndrome means
absorbtion of dose lger than 10 rad or greater in short time frame
32
how soon can you noticed symptoms of acute radiation syndrome
hours to weeks
33
what happens is acute whole body dose is >450 rad
50% of pop would die in 60 days without medical treatment
34
whole body means
head, trunk and major blood forming organs extending to the arms just below the elbow and the legs to just below the knees
35
whole body dose rate is
radiation level measured at a point of approx 30 cm or 1 ft from the source
36
blood forming organ syndrome needs how many rads
>100 rad to affect BM
37
blood forming organ syndrome is... and includes what organs... and symptoms
damage to cells that divide most rapidly and bm, spleen, lymphatic tissue and symptoms: internal bleeding, fatigue, bacterial infection, fever
38
Gi tract symotomys need how many rads and what does it do and symptoms
>1000 rads and damage to cells that are less rapid than hemopoeitic cells -affects lining of stomach and inestines -symptoms include nausea, vomiting, diarrhea, dehydration, electrolyte imbalnce, loss of digestion, bleeding ulcers
39
central nervous systen beeds how many rads to be damaged and symptoms
>5000 rads -cells that do not reproduce -affects nerve cells - death caused by internal bleeding, fluid, and pressure build up on brain
40
200-300 rads causes what
-reddening of the skin -hair loss via damaged follicles
41
125-200 rads to ovaries causes what
prolonged or permanent supression of menstruation in 50% of women
42
600 rad to testicles causes what
permanent sterilization
43
50 rad to thyroid causes what
benign tumors
44
what type of exposure is the human body better equipped to handel
chronic because there is more time to repair the cells and fewer cells that need repair at any given time
45
harder to know the affects in occupational exposure T/F
T
46
somatic effects that are prompt include
occur soon afteer exposed -hair fallin out afte 400 rad dose to scalp but will grow back
47
somatic effects that are delayed include
-takes place years after exposure -cataracts or cancer
48
can effect appear in future generations?
yes as a result of damage to the reproductive cells
49
is risk of future generation affect higher than somatic effect
smaller than somatic effects -dose limits for exposed person equally protect future generations