powerpoints- acid base/kidney Flashcards

1
Q

Break down of glomerular wall

A

increases permeability, makes more leaky

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2
Q

If acidosis -> respiration

A

hyperventilation -> more CO2 out of blood -> pH will rise

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3
Q

If alkalosis -> respiration

A

hypoventilation -> CO2 rises in blood -> pH will decrease

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4
Q

In kidney: If acidosis ->

A

reabsorb and produce HCO3- -> pH will rise

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5
Q

in kidney: If alkalosis ->

A

decrease reabsorption -> decrease in H+ excretion -> pH will decrease

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6
Q

hematuria

A

presence of abnormal numbers of red cells in urine

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7
Q

causes of hematuria

A
glomerular damage 
tumors which erode the urinary tract 
urinary tract stones
acute tubular necrosis 
upper and lower urinary tract infections
bladder catheter
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8
Q

Pyuria

A

presence of abnormal numbers of leukocytes

on pp- multilobed nuclei

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9
Q

cause of pyuria

A

infection in either the upper or lower urinary tract or with acute glomerulonephritis.

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10
Q

Squamous Epithelial Cells

A

cells from lining of renal tubular

on pp- egg shaped, small nucleus

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11
Q

types of casts

A
hyaline- youngest
waxy- oldest
fatty
WBC
RBC
epithelial 
granular
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12
Q

hyaline cast

A

protein

factors: low flow rate, high salt concentration, low pH

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13
Q

RBC casts

A

RBC stick together and form cast

suggests a glomerular or renal tubular injury

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14
Q

WBC Casts

A

acute pyelonephritis
glomerulonephritis
inflammation of the kidney

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15
Q

Bilirubinuria

A

liver malfunction, bile duct obstruction or excessive hemolysis
pp- Fine needle-like crystals

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16
Q

Crystalluria

A

calcium oxalate
triple phosphate crystals
amorphous phosphates

17
Q

Very uncommon crystals in crystalluria

A

cystine crystals
tyrosine crystals
leucine crystals

18
Q

Calcium oxalate crystals

A

most common kidney stone

on pp- looks like envelope

19
Q

Uric acid crystals

A

don’t form kidney stones
deposits in joints
gout

20
Q

Triple phosphate crystals

A

on pp- gold bars

21
Q

Cystinuria

A

on pp- stop signs

may precipitate out of the urine

22
Q

Cholesteroluria

A

on pp- flat squares

23
Q

renal cortex

A

on pp- Purple balls with clear surrounding

bowmans space is the clear

24
Q

distal vs proximal

A

distal look clearer

proximal have microvilli, look cloudy

25
renal medulla
vasa recta | different thickness
26
Glomerulosclerosis
destruction of glomeruli thickening of the capillary basement membrane glomerulus becomes sclerotic and nephron function is compromised
27
3 stages of glomerulosclerosis
Proliferate stage- increased number of cells, bowmans capsule is smaller Membronous stage- thinning and scarring Final stage- nephron cant function, wont filter- necrotic stage, all scar tissue with no capillary
28
Acute pyelonephritis
common in UTI | glomerulus will appear unaffected
29
Calculi
increased excretion of solutes such as calcium and when urine alkalinity, acidity, stasis, and/or concentration are favorable
30
Acute tubular necrosis
In a healthy tube, will be aligned and next to each other But are breaking down and out of order In the urine, would see epithelial cells