Post Partum Care Flashcards
Brexanolone is
Allopregnanolone
Given IV
Modulator of GABA-a receptors
Used to treat postnatal depression
Zuranolone is
Allopregnanolone
Neuroactive steroid
GABA-A receptor modulator
Pain management after c/s
Intrathecal diamorphine max 300 mcg or 3mg via epidural OR
Intrathecal morphine 100mcg + 15mcg fentanyl or 3mg morphine via epidural
Oral morphine sulfate, paracetamol and ibuprofen +/- dihydrocodeine
Tramadol or oxycodone if not sufficient
C/S wound care
Negative pressure wound therapy if BMI >35
Remove dressing 6 to 24 hours after
Risk of stress incontinence after c/s
4%
PPH target parameters
Hb >80 g/l
Plts >50 x 10(9)/l
PT and APTT <1.5 x normal
Fib > 2g/l
Use of FFP in PPH
1 unit for every 4 units RBC (15ml/kg) if PPH ongoing
> 15ml/kg if PT/APPT >1.5 x normal
Use immediately after thawing
Incidence of primary minor PPH
18% deliveries
Incidence of primary major PPH
1-5%
Define secondary PPH
Excessive vaginal bleeding 24h to 12 weeks postpartum
Incidence of secondary PPH in high income countries
0.47 - 1.44%
Active management of third stage reduces PPH by
RR 0.34
66%
Prevention of PPH for women without risk factors
Oxytocin 10 units IM for SVD
5 units slow IV for c/s
Prevention of primary PPH in women with risk factors
Syntometrine for SVD
Oxytocin + consider TXA for C/S
MDT for major PPH
Midwife in charge
Band 6 midwife
Obs reg
Anaesthetic reg
On call clinical haematologist
Porters
Alert consultant obstetrician, anaesthetist and blood lab
Resuscitation for minor PPH without shock
IV access
FBC, coag, G&S
HR, RR, BP every 15 mins
Warmed crystalloid infusion
Resuscitation for major PPH with ongoing bleeding or signs of shock
Assess airway
Start 15L oxygen
Continuous HR, RR, BP (use ECG)
Temp every 15 minutes
2 x cannulae
Cross match 4 units, FBC, coag, U&E, LFT
Keep warm and lie flat
Give blood if signs of shock or Hb <70 with ongoing bleeding
Give 2L warm crystalloid then 1.5L warm colloid pending blood
Catheter
HDU/ICU care
Consider art line