Post mortem examination Flashcards

1
Q

What medical questions can be answered using an autopsy?

A
  • confirming diagnosis
  • revealing a diagnosis
  • explaining unexplainable findings
  • investigating possible failings in medical care
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2
Q

What medico-legal questions can be answered on an autopsy?

A

Deaths that may involve:

  • violence
  • accidents
  • unexplained
  • occupation-related
  • suicides
  • deaths in custody
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3
Q

What steps does an autopsy involve?

A
  • Background information (pmhx, summary of clinical events)
  • external examination (general appearance)
  • internal examination (systems)
  • Further investigations (samples taken)
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4
Q

What information can be learned from the external examination

A
  • height/weight/bmi
  • scars
  • drains
  • IV lines
  • trauma
  • jaundice
  • cyanosis
  • clubbing
  • oedema
  • lymphadenopathy
    etc.
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5
Q

How is internal examination carried out?

A
  1. Evisceration
  2. organ dissection
    - macroscopic assessment
    - microscopic assessment
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6
Q

What are the common vascular pathologies seen on autopsy

A
  1. Thrombosis and infarction (e.g. heart, gut, brain)
  2. Embolism
  3. haemorrhage
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7
Q

What are the outcomes of MI

A
  • sudden death from arrhythmia or acute left ventricular failure
  • cardiac rupture through weakened necrotic muscle
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8
Q

What is an embolism?

A

A mass of material that can move through the vascular system and is capable of blocking the lumen

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9
Q

Name common causes of emboli

A
  • thrombus
  • air
  • fat
  • amniotic fluid
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10
Q

Name common causes of haemorrhage

A

from rupture of blood vessel due to:

  • under high pressure
  • congenital weakness
  • weakened by disease
  • eroded into
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11
Q

Give an example of a haemorrhage as a result of a vessel under high pressure

A

cerebral haemorrhage in hypertension

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12
Q

Give an example of a haemorrhage as a result of a vessel weakened congenitally

A

subarachnoid haemorrhage from rupture of cerebral artery aneurysm (berry aneurysm)

  • congenital weakness due to lack of elastic fibers
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13
Q

Give an example of a haemorrhage as a result of a vessel weakened by disease

A

Rupture of abdominal aortic aneurysm due to severe atheroma in the abdominal aorta causing weakening of vessel

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14
Q

Give an example of a haemorrhage as a result of a vessel being eroded into

A

Bleeding from a duodenal ulcer

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15
Q

How does pneumonia spread in the body and how does this effect the lungs?

A

Through the blood rather than airways

- largely confined to one lobe

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16
Q

How does bronchopneumonia spread in the body and how does this effect the lungs?

A

Spread through the airways

- tends to be more generalised appearance