Post-labor complications Flashcards

1
Q

RDS risk factors

A

Most important is prematurity, but other factors include male sex, perinatal asphyxia, maternal diabetes, and c-section without labor.

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2
Q

How does maternal diabetes increase the incidence of RDS?

A

Maternal hyperglycemia causes fetal hyperglycemia, which in turn triggers fetal hyperinsulinism. High levels of circulating insulin antagonize cortisol and block the maturation of sphingomyelin, a vital component of surfactant.

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