Populations Flashcards
3 to 1 ratio
AKA Mendelian ratio. Expressed in the F2 generation. 3 dominant to 1 recessive-displaying offspring.
Gene vs. allele
A gene is a stretch of DNA that can mutate into variations (eg, eye color). An allele is the variation (eg, blue eyes).
Phenotype
Expression of a trait. The phenotype is expressed through the action of enzymes and other structural proteins (which are encoded by genes).
Genotype
Individual’s genetic makeup
Complete dominance
Exhibited by the flowers in Mendel’s experiment. For any one trait, a diploid individual will have 2 chromosomes each containing a separate gene that codes for that specific trait.
These 2 chromosomes are homologous by definition.
Their corresponding genes are located at the same locus or position on respective chromosomes.
Each gene contributes an allele to the genotype. However- only one allele (the dominant allele)- is expressed.
If both alleles are dominant, then the dominant phenotype is expressed. If both alleles are recessive, then the recessive phenotype is expressed.
Heterozygous
AKA hybrid. An individual with a genotype having one dominant and one recessive allele is said to be heterozygous for the trait.
Law of Segregation
Mendel’s first law of heredity. Alleles segregate independently of each other when forming gametes. Any gamete is equally likely to possess any allele.
The phenotypic expression of the alleles is not a blend of the two, but an expression of the dominant allele (the principle of complete dominance).
Incomplete dominance
AKA partial dominance.
When a heterozygous individual exhibits a phenotype that is intermediate between its homozygous counterparts, the alleles are referred to as partial (incomplete) dominants.
Alleles showing partial dominance are represented with the same capital letter, and distinguished with a prime or superscript.
For instance, a cross between red flowered sweet peas and white flowered sweet peas may produce pink flowers. The genotype for the pink flowered individual would be expressed as either CC’ or CrCw.
Punnett square
For predicting genotypic ratios of offspring. Each offspring genotype is also equally likely.
Law of Independent Assortment
Mendel’s second law of heredity. States that genes located on different chromosomes assort independently of each other. In other words, genes that code for different traits (such as pea shape or pea color), when located on different chromosomes, do not affect each other during gamete formation. The closer they are on the chromosome, the more likely they will remain together.
Dihybrid cross
Make the assumption that genes for different traits are on separate chromosomes, and will assort independent of each other. The phenotypic ratio of a dihybrid cross is 9: 3: 3: 1.
Codominance
If the heterozygote exhibits both phenotypes, the alleles are codominant. Human blood type alleles are codominant because a heterozygote exhibits A and B antigens on the blood cell membrane.
Sex chromosomes
In humans, the 23rd pair of chromosomes establishes the sex of the individual, and each partner is called a sex-chromosome. Males are XY, females are XX.
Karyotype
Map of the chromosomes
Sex-linked
When a gene is found on the sex chromosome it is called sex linked.
Generally, in humans, the Y allele does not carry the allele for the sex-linked trait; thus the allele that is carried by the X chromosome in the male is expressed whether it is dominant or recessive. The female- who has 2 X chromosomes- ‘s genotype is found through the normal rules.
Barr body
In most somatic cells, one of the X chromosomes of the female will condense, and most of it’s genes will become inactive. The tiny dark object form is called the Barr body. These are formed at random, so the active allele is split about evenly among the cells. Nevertheless, in most cases, the recessive phenotype is only displayed in homozygous recessive individuals.
Carrier
A female may carry a recessive trait on her 23rd pair of chromosomes without expressing it. Such a recessive trait has a strong chance of being expressed in her male offspring regardless of the genotype of her mate, because the Y chromosome doesn’t contribute. See the Punnett square for hemophilia for more clarification.
Gene pool
The total of all the alleles in a population. Even if the ratio of individuals temporarily changes, as long as the gene pool remains the same breakdown, the population has not evolved.
Evolution
A change in the gene pool