Poppin' Pills Flashcards
___% of pts over 75 y.o. assess health as excellent or very good. Most have at least ___ chronic illness
39%
1
What are the most frequent chronic illnesses in geriatric population? (5)
arthritis 53% heart dz 35% CA 32% DM 22% HTN 72% M, 80% W
what is poly-pharmacy and what % of the geriatric population qualifies for this?
__ % of hospital pts have ADRs?
Taking 5+ medications
35.8% (44% M, 57% W)
28%
Poly-pharmacy is the __the leading cause of mortality in geriatric pts
5th
what are pts at increased risk for if they take multiple medications (5)
Hospitalization Functional and cognitive impairment Falls, frailty, delirium Mortality Noncompliance
___ decreases as we age and can cause medications to be excreted slower
GFR
How is absorption altered in the geriatric population?
Decreased gastric emptying
Increased gastric pH
Should you take calcium carbonate with food?
yes (needed for osteoporosis)
How is distribution in the geriatric population different?
increased body fat
decreased body water
decreased serum albumin
What are metabolic differences in the geriatric population?
Hepatic blood flow decreases with age
P450 activity decreases with age
Clearance decreases by 30-40%
“start slow, go slow”
How is elimination different in the geriatric population?
CrCl decreases ~8ml/min/decade
- decrease GFR
Decreased hepatic metabolism
**see specific examples on PPT
What are medication risks in the geriatric population?
Hospitalizations ADR more problematic Overdosing Inappropriate drugs Under-prescribing Poor adherence Inadequate monitoring
What drug should you avoid prescribing to geriatric pts?
anti-cholinergics
___% of pts missing medications for appropriate indications
58%
What is the STOPP and START criteria?
STOPP (Screening Tool of Older Persons’ potentially
inappropriate Prescriptions) –> over-prescribing
START (Screening Tool to Alert doctors to Right Treatment) –> under-prescribing