POP GEN Flashcards
Pop Gen
Study of evolution by
- determining genetic change btw pop
- establishing the most likely cause
Panmixia
single, randomly mixed pop where an ind is = likely to mate with any member of the opp sex
Allele Frequency
Prop of specific allele to ALL alleles in ALL ind in the pop
defines the pop gene pool
Genotypic Frequency
Proportion of a specific genotype relative to ALL genotypes in ALL ind in the pop
Hierarchy of genetic diversity
Ind- allelic, haplotypes, heterozygosity
Within pop- allelic, ave heterozygosity, ave # polymorphic loci
Among Pop- differentiation and genetic distance
Island Model
One mainland with migration to island
Stepping Stone Model
Ind pop only able to exchange genes with adj pop
Metapopulation Model
Ind move btw pop but popalso come and go over time
Hardy-Weinberg Model
null model of evolution
pop in genetic equilibrium
genotypic freq represented as a simple fn of allelic freq at a locus
HWE (in words)
freq of alleles and genotypes will remain constant over time in the absence of other evolutionary influences
HWE assumptions
- infinite and constant pop size
- no migration
- random mating
- no mutation
- diff genotypes= fitness
HWE (equation)
p^2 + 2pq + q^2
HWE p^2
dominant homozygous freq
HWE q^2
recessive homozygous freq
HWE 2pq
heterozygous freq