Polymyositis Pope Flashcards

1
Q

What is myositis?

A
  • Aka idiopathic inflammatory myopathy
  • Muscle weakness w/inflammation in muscle tissue
  • Systemic complications
  • Unknown cause
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2
Q

Clinical presentation of myositis

A
  • Proximal muscle weakness
  • Systemic symptoms of fatigue and anorexia
  • Skin rash w/dermatomyositis subset
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3
Q

Rashes of dermatomyositis

A

Gottron’s papules
Heliotrope rash
Shawl sign
Mechanic’s hands

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4
Q

CK and aldolase are specific to what tissue?

A

Muscle

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5
Q

AST and LDH are specific to which tissues?

A

Muscle and liver

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6
Q

ALT is specific to what tissue?

A

Liver

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7
Q

MC autoimmune antibody that occurs in myositis?

A

Anti-Jo-1

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