Polymyalgia Rheumatica Flashcards

1
Q

What is polymyalgia rhematica?

A

inflammatory rheumatologic syndrome

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2
Q

What is common epid of PMR?

A
  • Women

- Older than 50

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3
Q

What is PMR associated with?

A

15-20% patient with PMR have giant cell arteritis

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4
Q

What are symptoms and signs of PMR?

A
  1. Difficulty rising from seated or prone position
  2. Shoulder and hip girdle stiffness
  3. Muscle tenderness
  4. Shoulder/hip bursitis
  5. Oligoarthritis
  6. Acute onset
  7. Anorexia
  8. Low grade fever
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5
Q

What are possible DDx for PMR?

A
  1. Giant cell arteritis
  2. Early rheumatoid arthritis
  3. Hypothyroidism
  4. Fibromyalgia
  5. Polymyositis
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6
Q

What is the diagnosis of PMR based on?

A

history and elevated ESR and CRP

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7
Q

What bloods are order and what is found in PMR?

A
  1. ESR: elevated
  2. CRP: elevated
  3. FBC
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8
Q

What is the management of PMR?

A
  1. 1st line: corticosteroid e.g. prednisolone 12.5-25mg daily
    -calcium + vit D + bisphopsphonate
    -NSAID
  2. 2nd line: methotrexate and folic acid
    3, 3rd line: tocilizumab
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9
Q

How long does it take for PMR treatment to work?

A

Rapid improvement occurs within 24-72 hours with low dose prednisolone

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10
Q

What are possible complications of PMR?

A
  1. Chronic relapsing PMR
  2. Increased risk of infection secondary toc orticosteroid
  3. Osteoperosis secondary to corticosteroid
  4. DMT2 to corticosteroid
  5. Giant cell arteritis
  6. Etc
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11
Q

How long do patients need treatment for PMR?

A

2-3 years

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