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oncology > polycythemia vera > Flashcards

polycythemia vera Flashcards

1
Q

A patient presents with generalized pruritus worse after taking a hot bath. Labs show: increased hct, low MCV but no hypoxia. What is your working diagnosis?

A

polycythemia vera

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2
Q

A patient has low EPO but high hct What is your working diagnosis?

A

Polycythemia vera

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3
Q

Give 3 conditions that has increased RBC count but low MCV:

A

Polycythemia vera, thalasemia and hypoxia

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4
Q

what is the most common cause of death in polycythemia vera?

A

Thrombosis. the vessels get clogged uo with increased hct increasing the viscosity of the blood.

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5
Q

what is the mainstay treatment for polycythemia vera?

A

phlebotomy

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6
Q

what is the most likely longterm transformation in patients with polycythemia vera?

A

they can develop myelofibrosis

- see tear drop shaped cells and nucleated RBCs on PBS

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7
Q

what is the treatment for myelofibrosis?

A

lenalidomide (TNF inhibitor)

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oncology (4 decks)

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