breast cancer

Question 1

at what age is mammographic screning recommended for the general population?

Answer 1

50 years old

Question 2

at what age is mammographic screening recommended for those with significant family history?

Answer 2

40 years old

Question 3

what can be used to prevent breast CA in those with significant family history of breast CA?

Answer 3

Tamoxifene or Raloxifene (SERMs)

Question 4

SERMS is agonist to what organs?

Answer 4

Endometrium = risk of endometrial CA
bone = benefits osteoporosis
clotting factors

Question 5

MOA of trastuzumab

Answer 5

mab that removes HER2/neu positive cells

Question 6

if the FNAB turns out postitive for Breast CA, what will you do next?

Answer 6

sentinel LN biopsy

Question 7

if the sentinel LN biopsy comes out positive what will you do next?

Answer 7

axillary LN biopsy

Question 8

what is the most common adverse effect of aromatase inhibitors?

Answer 8

osteoporosis

- it decreases estrogen production and inhibits osteoblasts

Question 9

Which treatement lowers the mortality the most in breast CA?

Answer 9

adjuvant chemotherapy