Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Haematology > Polycythaemia Vera > Flashcards

Polycythaemia Vera Flashcards

1
Q

What is polycythaemia vera?

A

Myeloproliferative disorder of clonal proliferation of a marrow stem cell leading to an increase in red cells often accompanied by overproduction of neutrophils and platelets

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What is the management for polycythaemia vera?

A

Aspirin
Venesection
Chemotherapy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What is complication of chemotherapy in PV?

A

Transformation to acute leukaemia (5-15% of patients)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What are complications of PV?

A

Thrombo-embolic events
Transformation to acute leukaemia (5-15%)
Transformation to myelofibrosis (5-15%)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

A patient presents with gingival bleeding, confusion and fluctuating GCS. Diagnosed with PV. Recently started on chemotherapy. O/E - pétéchial rash, painless hepatosplenomegaly. Bloods - thrombocytopenia, increased PT and APTT. What is the diagnosis?

A

Patient likely has DIC, due to acute promyelocytic leukaemia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly

Haematology (4 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions