Polycystic kidney disease Flashcards

1
Q

ARPCKD

A

cysts originate from the renal collecting ducts while in autosomal dominant ds the cysts can arise anywhere in the nephron. most common inherited renal cystic ds in infancy and childhood

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2
Q

ADPCKD

A

this causes progressive kidney enlargement.

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3
Q

ADPKD clinical features

A

most patients are asymptomatic. flank, back and or abdominal pain. uti and renal stones occur. hematuria. HTN, intracerebral aneurysm, hepatic cysts

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4
Q

ADPKD investigations

A

US is currently the most widely used diagnostic technique for dx of ADPKD. CT and or MRI are not routinely used however change in kidney volume by sequential MRI has been found to correlate inversely with the where the filtration rate and provide a growth rate signature for patients.

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