Polycystic kidney disease Flashcards
ARPCKD
cysts originate from the renal collecting ducts while in autosomal dominant ds the cysts can arise anywhere in the nephron. most common inherited renal cystic ds in infancy and childhood
ADPCKD
this causes progressive kidney enlargement.
ADPKD clinical features
most patients are asymptomatic. flank, back and or abdominal pain. uti and renal stones occur. hematuria. HTN, intracerebral aneurysm, hepatic cysts
ADPKD investigations
US is currently the most widely used diagnostic technique for dx of ADPKD. CT and or MRI are not routinely used however change in kidney volume by sequential MRI has been found to correlate inversely with the where the filtration rate and provide a growth rate signature for patients.