Polyarteritis Nodosa Flashcards
1
Q
What is the pathology of PAN?
A
A medium-sized arteries with necrotizing inflammation leading to aneurysm formation.
2
Q
What condition is PAN associated with?
A
Hepatitis B
3
Q
What group of people is PAN more common in?
A
Middle aged males
4
Q
What are some signs/symptoms of PAN?
A
- Fever, malaise, arthralgia
- Weight loss
- Hypertension
- Mononeuritis multiplex, sensorimotor polyneuropathy
- Testicular pain
- Livedo reticularis
- Haematuria, renal failure
5
Q
Hepatitis B serology is positive in what % of patients?
A
30%
6
Q
In classic PAN, what autoantibodies are found in 20% of patients?
A
p-ANCA
