Drug-Induced Lupus Flashcards
1
Q
What is the difference between Drug-induced Lupus and SLE?
A
Drug-induced lupus you get the Skin, MSK and Lung involvement.
But rarely get the nervous system and renal system involvement like you would in SLE.
2
Q
What are some features of Drug-induced lupus?
A
- Arthralgia
- Myalgia
- Skin (e.g. malar rash) and pulmonary involvement (e.g. pleurisy) are common
3
Q
What autoantibody tests can you do to check for drug-induced lupus?
A
- ANA positive in 100%, dsDNA negative
- anti-histone antibodies are found in 80-90%
4
Q
What 2 drugs are the most common causes of drug-induced lupus?
A
- Procainamide
- Hydralazine
5
Q
What 3 drugs can also cause drug-induced lupus, but less commonly do so?
A
- Isoniazid
- Minocycline
- Phenytoin
6
Q
What is this?
A
The malar rash of drug induced lupus.
