Podcast 3 Flashcards
What is dura mater in CNS inverted by
Sinuvertebra nerves (SN)
What does the SN supply
Goes through the IVD to dura and post and longitude ligaments and annulus fibrosis
What happens towards the midline of dorsal dura
Becomes insensitive
What nerves have intrinsic innervation at PNS
Peripheral nerves
nerve roots
autonomic nervous system
Called nervi nervorum
Three facts about nervi nevorum at PNS
1) Innervation ⬆️ capacity of CT to protect fragile nerves
2) Has neuropeptides to mediate inflam response
3) Source of symotoms + contribute to sensory imput
Name seven ways the NS response to elongation
1) Development of tension with in tissue
2) Movement of NS
3) Resting position = Nerves curled up and lose
4) Movement and elongation= Nerves Uncurled + loose slack
5) Amount of glide reached limits= Neural tension ⬆️
6) Neural tissue elongates under constant load= Returns to original lenght if elastic limit does not exceed
7) Gliding depends on tension point and sequence of movement
Elaborate on movement of NS
Gross (relation to mechanical interphase)
Intraneural
Generalised:
-Movement of body parts in neutral= ⬆️ mvt in NS and ⬇️tension
-Movement of body parts in tension position= ⬇️mvt in NS and ⬆️tension
Name six facts about the axonal transport of NS
1)neuro physiology process ralated to mvt
2) Intraneural communication
3)Intracellular movement in axoplasm
4) Constant and controlled movements
5) Transport depends on: supply from blood + enhanced by axoplasm
6) 2 main flows:
anterograde- cell ➡️ perpheries
Retrograde- target➡️cell
And then six facts about blood supply of NS
1) Neurophysiology process related to movement
2) Multiple supply
3)Adaptability to mechanical stress
4)Intraneural bloodflow
5)Mobile and intact circulation
6)Sudden movement resulting strong tesion = alter circulation
Lead ➡️hypoxia and nerve damage
Six ways NS is protected
1) meylin sheath
2) Wavy appearance of neuron
3) CT resist compression
4) Diffusion barrier fights infection
5) Neurovascular supply coiled
6) Innovation of CT= warning signs
Five types of PNS injuries
Compression friction stretch chemical irritation Illness
Name three key processes related to injury in PN
Altered bloodflow
altered axoplasm flow
development: altered impulse generating sites (AIGS)
Elaborate on altered bloodflow (injury)
Altered pressure gradient:
Venous stasis(hypoxia)
Oedamatous syage (nerve swell)
Fibrous stage: ⬆️ fibrous tissue
Elaborate on AIGS
Axonal injury
myelin sheeth removed
more receptors at site
sensitive to PN
What is the biomechanical response of NS to tensile force
Loss of integrity of peripheral nerves at 20% elongation
Bloodflow ends at 15% elongation
