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CNS > PNS pharmacology > Flashcards

PNS pharmacology Flashcards

1
Q

Which drugs affect cholinergic transmission?

A

Muscarinic agonists/antagonists
Ganglion stimulating and blocking drugs
Neuromuscular blocking drugs
Anticholinesterase

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2
Q

How do muscarinic agonists work? When might they be used?

A

Stimulate postganglionic muscarinic receptors
CV system - slow and decrease CO
Smooth muscle - contracts (mostly), some dilation via vasodilation
Exocrine glands
Eye

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3
Q

What are the adverse effects of muscarinic receptors?

A

GI cramping
Salivation
Bradycardia

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4
Q

How do muscarinic antagonists work?

A

Inhibit postganglionic muscarinic receptors

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5
Q

What effect do muscarinic antagonists have?

A

Increase heart rate
Decrease salivary, bronchial and gastric secretion
Bronchodilation
Decreased GI motility

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6
Q

What are the adverse effects of muscarinic antagonists?

A

Tachycardia
Dry mouth
Constipation

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7
Q

Ganglion stimulating and blocking drugs have systemic and complex effects. Why?

A

Affect both sympathetic and parasympathetic ganglia

Rarely used!

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CNS (15 decks)

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