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Pharmacology > PNS > Flashcards

PNS Flashcards

1
Q

General side effects of PNS agonists

A 
§ salivation
§ sweating
§ bronchoconstriction
§ bradycardia
§ diarrhea
§ bronchial mucus secretion
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2
Q

Name PNS agonists

A

Neostigmine, edrophonium, donepezil, pilocarpine, malathion, rivastigmine

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3
Q

Method of action of edrophonium

A

Reversible acetylcholine esterase inhibitor

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5
Q

Method of action of malathion

A

Irreversible acetylcholine esterase inhibitor

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6
Q

Method of action of donepezil

A

Reversible acetylcholine esterase inhibitor in brain

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7
Q

Method of action of rivastigmine

A

Acetylcholine esterase inhibitor

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8
Q

Method of action of pilocarpine

A

Non-selective muscarinic receptor agonist

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9
Q

Use of neostigmine

A

§ Muscle weakness
§ treatment of myasthenia gravis
§ post-surgical ileus

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10
Q

Use of edrophonium

A

§ muscle weakness
§ diagnosis of myasthenia gravis
§ post-surgical ileus

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11
Q

Use of pilocarpine

A

§ Dry mouth

§ glaucoma

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12
Q

Use of malathion

A

Head and body lice

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13
Q

Use of donepezil

A

Alzheimer’s

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14
Q

Use of rivastigmine

A

Alzheimer’s and mild dementia

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15
Q

Unusual side effect of pilocarpine

A

Vasodilation

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16
Q

Administration of neostigmine

A

IV

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17
Q

Admin of edrophonium

A

Oral, IV

18
Q

Admin of pilocarpine

A

Oral, eye drops

19
Q

Admin of malathion

A

Oral, topical, inhalation

20
Q

Admin of donepezil

A

Oral

21
Q

Admin of rivastigmine

A

Oral, transdermal patch

22
Q

General side effects of PNS antagonists

A

Dry mouth

23
Q

Name PNS antagonists

A

§ atropine
§ ipratropium bromide
§ hyoscine

24
Q

Method of action of PNS antagonists

A

Anticholinergic, meaning they competitively bind to muscarinic receptors blocking acetylcholine

25
Q

Use of atropine

A

§ bradycardia
§ organophosphate poisoning (insecticides)
§ to inhibit mucus and salivary glands
§ bronchoconstriction

26
Q

Use of ipratropium bromide

A

§ COPD

§ diarrhea

27
Q

Method of action of neostigmine

A

Reversible acetylcholine esterase inhibitor

28
Q

Use of hyoscine

A

§ IBS

§ diarrhea

29
Q

Atropine side effects

A 
Dry mouth
Tachycardia
Constipation
Blurred vision
Urine retention
30
Q

Ipratropium Bromide side effects

A

Dry mouth

Sedation

31
Q

Hyoscine side effects

A 
Dry mouth
Tachycardia
Constipation
Blurred vision
Urine retention
32
Q

Atropine admin

A

IV

Topical

33
Q

Hyoscine admin

A 
Oral
Subcutaneous
Opthalmic
IV
Transdermal patch
34
Q

Ipratropium bromide admin

A

Inhalation

Pharmacology (4 decks)

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