PNS 1 Flashcards
Neurotransmitter examples
- Acetylcholine
- Norepinephrine
- Epinephrine
Autonomic nervous system
Innervates organs with involuntary movements
- -sympathetic (fight or flight)
- parasympathetic (rest and digest)
Somatic nervous system
Innervates organs with voluntary function
- under conscious control
Ex: skeletal M,sphincter tone
Acetylcholine is released from?
Presynapitc neurons
Acetylcholine is broken down by?
Cholinesterases
Norepinephrine is released from?
Synaptic nerve endings
Epinephrine is released by?
Adrenal glands
Cholinergic receptors
- Nicotinic (Ionotropic receptor)
- Muscarinic (metabotropic receptor)
Autonomic Drugs are Classified as Either:
- Mimetics
- Lytics
Mimetics
Drugs that stimulate autonomic effects
- parasympathomimetics
- sympathomimetics
Lyrics
Drugs that block autonomic effects
- parasympatholytic
- Sympatholytic
Autonomic Drugs can be:
- Direct acting
- Indirect acting
Direct acting
- Agonist and antagonist
- act directly on the receptor
-ex: cholinergic Agonist, adrenergic antagonist
Indirect acting
Interaction with substances other than the receptor
– EX: acetylcholinesterase inhibitors
