Pneumonia/ TB Flashcards
What is pneumonia?
Acute inflammation of the lung parenchyma
May be infectious or not infectious
How do microbes enter the lungs?
Inhalation or aspiration of secretions from the oropharynx
Where can the microbes also enter besides the lungs?
Bloodstream
What are normal defenses against pneumonia?
Cough reflex
Pulmonary macrophages
Nasopharyngeal defenses
Cilia lining the respiratory tract
What do endotoxins cause?
Congestion and edema
What releases endotoxins?
Microbes
What happens to the alveoli and bronchioles when they are invaded?
Inflammation
Immune response
What are the different ways pneumonia is acquired?
Bacterial
Viral
Fungi
Aspiration
How does bacterial pneumonia occur?
Entrance to the lungs via bloodstream
Aspiration of resident bacteria
Person to person via droplet
Characteristics of bacterial pneumonia?
Damage cells and usually in one lung
Even distribution of microbes
What is the most common of bacterial pneumonia?
Streptococcus pneumoniae
What is a hospital associated bacterial pneumonia?
Staph aureus
What is walking pneumonia?
Caused by mycoplasmas
Symptoms similar to but milder than those of bacterial or viral pneumonia
Walking pneumonia typically affects what population?
School-age children and adults under 40.
How does viral pneumonia occur?
Enter from upper airway and infiltrate alveoli in one or both lungs
Characteristics of viral pneumonia?
Invade cells and kill them, send out debris
Patchy distribution
Influenza and adenovirus
What are some other causes of infectious pneumonia?
Fungi and protozoa
What is aspiration pneumonia?
Infectious or non-infectious
Chemical injury and inflammatory response
What are some causes of aspiration pneumonia?
Food
Emesis
Reflux
Hydrocarbons
What are some complications of pneumonia ?
Bronchiectasis Pleuritis Pleural effusion Lung abscess Empyema
What are risk factors for pneumonia ?
Infants Elderly HIV/AIDS Cancer, organ transplant Chronic illnesses- DM, cardiac, respiratory Endotracheal intubation (VAP) NG tubes Smoking, alcoholism
What is VAP?
Ventilator Associated Pneumonia
Why are infants at risk?
Immature immune system
Why are the elderly at risk?
Decreases cough and gag
What are some ways of prevention of pneumonia?
Early identification and appropriate treatment
Vaccines
What are some types of vaccines for pneumonia?
Pneumococcal PCV13- children under 2 PPSV23- adults Hib- children under 2 Influenza
What are some clinical manifestations of pneumonia?
Fever, chills Cough (productive, purulent) Chest pain Blood-tinged sputum SOB Decreased appetite Cyanosis Crackles Wheezing