Pneumonia Flashcards

1
Q

what is pneumonia

A

infection of the lung tissue

causes inflammation of the lung tissue and sputum in the airways and alvoli

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2
Q

classification of pneumonia

A
  1. CAP (community acquired pneumonia)
  2. HAP (hospital acquired pneumonia) *develops 48 hours after admission to hospital
  3. aspiration pneumonia (after inhaling foreign material e.g. food)
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3
Q

how does pneumonia present?

A

Shortness of breath
Cough productive of sputum
Fever
Haemoptysis (coughing up blood)
Pleuritic chest pain (sharp chest pain worse on inspiration)
Delirium (acute confusion associated with infection)
Sepsis

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4
Q

signs of pnuemonia

A
Derranged vital signs (sepsis)
Tachypnoea (raised respiratory rate)
Tachycardia (raised heart rate)
Hypoxia (low oxygen)
Hypotension (shock)
Fever
Confusion
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5
Q

O/E pnuemoina

A

Bronchial breath sounds. These are harsh breath sounds equally loud on inspiration and expiration. These are caused by consolidation of the lung tissue around the airway.

Focal coarse crackles. These are air passing through sputum in the airways similar to using a straw to blow in to a drink.

Dullness to percussion due to lung tissue collapse and/or consolidation.

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6
Q

CURB-65

A

CURB-65 scoring system in hospital (CRB-65 out of hospital)

C – Confusion (new disorientation in person, place or time)
U – Urea > 7
R – Respiratory rate ≥ 30
B – Blood pressure < 90 systolic or ≤ 60 diastolic.
65 – Age ≥ 65

it predicts mortality and guide if hospital admission is appropriate.

Score 0/1: Consider treatment at home
Score ≥ 2: Consider hospital admission
Score ≥ 3: Consider intensive care assessment

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7
Q

what are the common causes of pneumonia?

A
Streptococcus pneumoniae (50%)
Haemophilus influenzae (20%)

Moraxella catarrhalis in immunocompromised patients or those with chronic pulmonary disease

Pseudomonas aeruginosa in patients with cystic fibrosis or bronchiectasis

Staphylococcus aureus in patients with cystic fibrosis

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8
Q

atypical pneumonias

A

caused by an organism that cannot be cultlured in the normal way or detected using ram stain

they do not respond to penicillin

can be treated with macrolide (clarithromycin), fluroquinolones (levofloxacin) or tetracyclines (doxycyline0

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9
Q

legionella pneumonphilia

atypical

A

infected water supplies or air conditioning units.

can cause hyponatraemia (low sodium) by causing an SIADH.

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10
Q

mycoplasma pneumonia

atypical

A

milder pneumonia
erythema multiforme “target lesions”
neurological symptoms

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11
Q

chlamydophila pneumonia

A

school aged child

moderate - chronic pneumonia and wheeze

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12
Q

coxiella brunetti (Q fever)

A

exposure to animals and bodily fluids

farmer with flu like illness

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13
Q

chlamydia pscittaci

A

contact with infected birds

parrot owner

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14
Q

fungal pneumonia

A

Pneumocystis jiroveci (PCP) pneumonia occurs in patients that are immunocompromised. (poorly controlled or new HIV with a low CD4 count)

subtly with a dry cough without sputum, shortness of breath on exertion and night sweats.

Treatment: co-trimoxazole (trimethoprim/sulfamethoxazole) known by the brand name “Septrin”.

Patients with low CD4 counts are prescribed prophylactic oral co-trimoxazole to protect against PCP.

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15
Q

investigations for pneumonia

A

bedside: sputum cultures
bloods: FBC (WCC), U+E (urea), CRP (raised), blood cultures, legionella and pneumococcal urinary antigens
imaging: CXR (consolidation)

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16
Q

treatment of pneumonia

A

resistance

moderate-severe / septic = IV abx then change to oral if improvement

mild CAP: amoxicillin / macrolide 5 day course

mod-severe CAP: 7-10 dual antibiotics (amoxicillin and macrolide)

17
Q

pneumonia complications

A
Sepsis
Pleural effusion
Empyema
Lung abscess
Death
18
Q

HAP mx

A

gram-ve enterobacteria
pseudomonas
s.aureue

  • also in care home
  • developed with 48hrs
19
Q

immunocompromised pneumonia

A
strep
CMV
HSV
pneumocystis
aspiration pneumonia
20
Q

pneumonia buzzwords

  1. klebsilella
  2. pseudomonas
  3. legionella
  4. jirovecci
  5. staph aureus
A

each klebsiella- elderly and alcoholic
*caveatting pneumonia

pseudomonas
immunocompromised in hospital. CF** (common in bronchiectasis)

legionella
jacuzzi, water-tanks
*clarithromycin
*hyponatraemia
*abnormal LFT
*diagnose with urinary antigen

pneumocystis jirovecci (fungus)
AIDS / HIV
cotrimoxazole

staph aureus
post-infective pneumonia

aspiration pneumonia
stroke, post-surgical

21
Q

pack years

A

20 in a pack
pack every day for a year = 1 pack year

2 packs a day for 40 years = 80 pack year

22
Q
  1. klebsiella
  2. pseudomonas
  3. legionella
  4. pneumocystic jirovecci
  5. staph aureus
A

Klebsiella- Elderly and Alcoholics
Chest X-Ray may show a cavitating pneumonia

Pseudomonas- Common in bronchiectasis and Cystic Fibrosis

Legionella- Think WATER TANKS (AC, swimming pools, hot tubs etc.) & Recently travelled
Bloods will generally show hyponatraemia
Abnormal LFTs
Lymphopenia
Diagnosis by Urinary Antigen
Treatment – Clarithromycin

Pneumocystis Jirovecci – Immunocompromised patients (THINK HIV)
Exertional dyspnoea and low sats
Inhibits folate
Minimal CXR findings
Dry cough
Treatment is co-trimoxazole (co-amoxiclav and trimethoprim)

Staph Aureus- post infection