Pneumology Flashcards
Feline asthma
Peripheral eosinophilia
17 - 46%
Do not correlate with airway eosinophilia
Trzil 2019
Feline asthma
Lack of RX abnormalities
Up to 25%
Trzil 2019
Feline astha
BALF cutoff
17% eosinophils
Non specific (parasitisme Aerulo, dirofilaria, toxocara)
Trzil 2019
Feline asthma
Chronic use of salbutamol
S-Enantiomere accumulates, promotes proinflammatory, bronchiconstriction
Healthy cat : neutrophilic inflammation
Asthmatic : exacerbate eosino airway inflammation
Trzil 2019
Feline asthma
Alternative treatment
Omega 3: ↓ airway hyperresponsiveness, no effect on BALF
Idem for inhaled lidocaine
ITK : ↓ BALF eosinophilia
Trzil 2019
Feline asthma
Non effective treatment
Leucotriene antagonist
Cetirizine
Cyproheptadine (5ht antagonist)
NAC inhaled : bronchospasm
Doxycycline
Trzil 2019
Feline inflammatory bronchial disease
Clinic presentation
Emergency more frequent FA
Nasal discharge more frequent in CB (20%)
Grotheer 2020
Feline inflammatory bronchial disease
Paraclinic
Eosinophilia FA (40%) > CB (25%)
Erythrocytosis FA = CB (30%)
Grotheer 2020
Epiglottic retroversion
Etiology
Epiglottic fracture, malacia
Hypothyroidism peripheral neuropathy
80% associated / secondary : BSOR, tr collapse, laryngeal paralysis, laryngeal saccule eversion
Skerrett 2015
Epiglottic retroversion
Epidemiology
Yorkshire, cocker, pekingese, pug
60% > 8y
Sketerrett 2015
Epiglottic retroversion
Complication
Mst
Frequent breakage of pexy (50%), aspiration pneumonia (33%)
Mst 875 days
Euthanasia for worsening resp
Skerrett 2015
Pneumocystis
Immunideficiency ?
Dachshunds : T and B cell immunodeficiency
Ckc : not confirmed but suspected (affection of littermate)
Often intercurrent disease : demodicosis, distemper
Weissenbacher 2018
Pneumocystis
Age ?
Range 6m - 6y
Med 1y
Dashchunds often < 1y
IPF
Pulmonary hypertension
WHWT diseased : 20 - 60 %
Laurila 2020
IPF
MST ?
11 m after diagnosis
acute exacerbation (alveolar diffuse damage) : grave prognosis, 5 / 15 dogs in a study
Laurila 2020