PMOC 2 SANITATION Flashcards
Application to living tissue for preventing infection
Antisepsis
Chemical or physical treatment that destroys most vegetative microbes or viruses, but nut spores, in or on inanimate surfaces
Disinfection
Destruction or marked reduction in the number of activity
of microorganisms
Decontamination
Reduction of microbial load on an inanimate surface to a level considered acceptable for public health purposes
Sanitation
Kills nonsporulating microorganisms by hot water or steam at 65-100°C
Pasteurization
Kill or remove all types of microorganisms, including spores, and usually including viruses with an acceptably low probability of survival
Sterilization
introduced antiseptic principles and phenol
Joseph Lister
Paul Ehrlich introduced
Salvarsan/magic bullet/Compound 606
First treatment for syphillis
Salvarsan
Most successful anti-infective agents
Mercury, Arsenic, Antimony
sleeping sickness treatment
Atoxyl (Sodium Arsanilate and Arsphenamine)
Anti infectives classification
- Chemical types of the compound
- Biological properties
- Therapeutic indication
antibacterial potencies of the primary alcohols (against test cultures of Staphylococcus aureus) increase with molecular weight until the __-carbon atom octanol is reached
8
one oxygen atom is capable of solubilizing _______ atoms in water
seven or eight carbon
Astheprimaryalcoholchainlengthincreases,vanderWaals interactions increase, and the ability to penetrate microbial membranes _____.
increases
Aswatersolubilitydecreases,theapparentantimicrobial potency ____ with molecular weight.
diminishes
Branching of the alcohol chain _____ antibacterial potency; weaker van der Waals forces brought about by branching do not penetrate bacterial cell membranes as efficiently
decreases
Clear, colorless, volatile liquid
Ethyl alcohol
Burning taste, pleasant odor
Rectified spirit
Flammable, miscible with water in all proportions
Wine spirit
Soluble in most organic
solvents
Grain alcohol
Prepared by sulfuric-acid –
catalyzed hydration of ethylene
Spiritus vini rectificatus
It inhibits alcohol dehydrogenase
Fomepizole