PMI02-2001 Micro-organism, structure & function Flashcards

1
Q

What does TSE stand for?

A

Transmissible spongey encephalopathies

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2
Q

What are TSEs?

A

Infective proteins as they affect the structure of other proteins
These proteins come together to form plaques or sponge-like lesions in the brain

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3
Q

How are TSEs transmitted?

A

Via prions- misfolded proteins that are expressed on neurones in the body and are associated with neurodegenerative disease
It a normal prion comes into contact with a misfolded one, it causes transmission of infection

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4
Q

Are bacteria, eukaryotes and viruses visible in light microscopes?

A
Bacteria= yes
Eukaryotes= yes
Viruses= no
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5
Q

Are bacteria, eukaryotes and viruses capable of free growth?

A
bacteria= some are
eukaryotes= yes
viruses= no
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6
Q

Can cell division of bacteria, eukaryotes and viruses make new cells

A
bacteria= yes
eukaryotes= yes
viruses= n/a
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7
Q

Are bacteria, eukaryotes and viruses metabolically active?

A
bacteria= yes
eukaryotes= yes
viruses= no
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8
Q

Are genes separated from the cytoplasm by membrane in bacteria, eukaryotes and viruses?

A
Bacteria= no
eukaryotes= yes
viruses= n/a
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9
Q

What is in genome in bacteria, eukaryotes and viruses?

A
bacteria= DNA
eukaryotes= DNA
viruses= DNA/RNA
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10
Q

Why are viruses referred to as obligate intracellular parasites?

A

They use a host cell’s machinery to reproduce

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11
Q

What is positive RNA?

A

Can be used directly for translation by acting as mRNA

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12
Q

What is negative RNA?

A

Needs to be transcribed first

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13
Q

What is the protein coat of a virus called and what is its purpose?

A

capsid

protects the nucleic acid

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14
Q

What are naked viruses?

A

They have the protein coat with the DNA inside

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15
Q

What are enveloped viruses?

A

They are packaged in a plasma membrane from the host cell

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16
Q

How do viruses replicate?

A

Host cells release chemokines
The virus will then attach to host cell receptors via the glycoprotein receptor on the viral cell and release its nucleic acids into the host cell