PM changes and artefacts Flashcards

1
Q

what is algor mortis

A

cooling after death

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2
Q

which cells have the lowest resistance to hypoxia?

A

brain and spinal cord (4mins)

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3
Q

Which cells have the greatest resistance to hypoxia?

A

bone and corneas (48hrs)

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4
Q

PM artefact that occurs following resuscitation attempt (incl. masks/intubation) against buccal mucosa are which type of injury?

A

mucosa of cheek against teeth = abrasion

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5
Q

Person who had MI in street and ambulance attempted CPR is found to have abrasions to face and a perforated stomach - explain this.

A

Abrasions from fall to ground

Stomach can tear when pressure applied during chest compressions, especially when stomach is full.

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6
Q

bacteria favours which kind of putrefaction?

A

wet putrefaction is favoured by bacteria

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7
Q

Adipocere is favoured in dry conditions - true or false?

A

false
adipocere is favoured in wet conditions
mummification favoured in dry conditions

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8
Q

A foetus lost to intra-uterine death will have which sign of putrefaction?

A

maceration of foetus due to sterile but wet environment of placenta.

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9
Q

When determining the PMI, the rate method observes what?

A

Rate method observes/measures changes which occur at a known rate.
E.g. vitreous K+, rigor, cooling, putrefaction, lividity

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10
Q

What does the concurrence method use in determining PMI?

A

Events which occurred at known times e.g. watch which stopped by blow, digestion of meal, or CCTV footage.

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11
Q

algor mortis is a good indicator of PMI after 24hrs - true or false

A

false

algor mortis is a good indicator of PMI in first 24hrs

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12
Q

What do you need to bear in mind when using cooling to determine PMI?

A

Should only be used in cool and temperate climates.
The body temperature at time of death is unknown and can be higher/lower depending on CoD.
The environmental temperature during cooling period has likely fluctuated.

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13
Q

Newton’s cooling curve shifts left when?

A

Curve shifts left in hypothermia, thin people, cool climates

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14
Q

Newton’s cooling curve shifts right when?

A

Shifts right in hyperpyrexia, warm climate, heavy clothing,.

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15
Q

The Henssge nomogram allows correction for…?

A

body weight, clothing, drafts, water

factors applied to body weight

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16
Q

When can Henssge nomogram NOT be used?

A
Strong heat source nearby
Cooling source nearby
Underlying surface conducts away heat (metal table)
Abnormal body temp. at death
Body has been moved
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17
Q

What does Henssge nomogram assume?

A

normal body temp at time of death and no change in cooling conditions.

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18
Q

What are the stages of muscle flaccidity?

A
  1. Primary flaccidity
  2. Rigor mortis
  3. Secondary flaccidity
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19
Q

Primary flaccidity is permanent - true or false

A

false
primary flaccidity = no tone
secondary flaccidity = permanent

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20
Q

rigor is postponed in freezing - true or false

A

true

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21
Q

Describe the muscle stiffening that occurs in hot temperatures.

A

accelerates rigor process

protein coagulation and shortening of muscles -> pugilistic posture

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22
Q

In life, formation of actin-myosin bridges stimulates muscle contraction. How is this affected in death?

A

Ca2+ still floods into cells and the actin-myosin bridges form however they cannot relax due to lack of ATP (required for breakdown) -> sustained contraction.

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23
Q

Fully formed rigor can be broken and re-form - true or false

A

false

fully formed rigor if ‘broken’ by force (undressing) will not reform

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24
Q

Partially formed rigor will continue to form even if broken - true or false

A

true

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25
Q

What factors effect the rate of rigor development?

A

onset/duration depend on:
environmental temperature
muscle activity prior to death

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26
Q

Rapid onset of rigor is associated with shorter duration - true or false

A

true

Rapid onset of rigor is associated with short duration (will lessen faster)

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27
Q

rigor develops in smallest muscles first then larger muscle groups affected next - true or false

A

FALSE
rigor develops simultaneously in all muscles
smaller muscles groups are COMPLETELY involved earlier vs. larger muscles and this passes off (putrefaction) in the same sequence

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28
Q

onset of rigor mortis is a useful indicator of PMI - true or false

A

false

onset of rigor is an unreliable indicator of PMI

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29
Q

What is the average time until first appearance of rigor mortis?

A

first appearance on average 3hr pm

30
Q

Rigor is fully established on average by 8hrs PM, but what is the range in which this can occur?

A

fully established by 8hrs but range is 2-20hrs

31
Q

How long does rigor often last for?

A

24-36hrs

32
Q

Why does muscle activity or starvation prior to death hasten rigor?

A

glycogen stores are depleted

33
Q

What situations hasten rigor onset?

A

high environmental temp
muscle activity or starvation prior to death
septicaemia
children, elderly

34
Q

you need to be careful not to confuse intensity of rigor with…?

A

degree of development
e.g., stronger intensity of rigor in strong adult males vs. elderly woman but this does not mean it is further ahead in process

35
Q

stiffening that occurs at moment of death and persists into period of rigor mortis is known as ?

A

cadaveric spasm - rare, instantaneous form of rigor

36
Q

Rule of thumb: warm + flaccid =

A

warm + flaccid = dead <3hrs

37
Q

Rule of thumb: warm + stiff =

A

warm + stiff = dead 3-8hrs

38
Q

Rule of thumb: cold + stiff =

A

cold + stiff = dead 8-36hrs

39
Q

Rule of thumb: cold + flaccid =

A

cold + flaccid = dead >36hrs

40
Q

what is lividity?

A

the gravitational settling of liquid blood in capillaries - seen as purple discolouration in dependent areas

41
Q

punctate haemorrhage is seen in which type of lividity?

A

punctate haemorrhage within intense lividity

42
Q

what is lividity a good indicator of?

A

position of body since death

43
Q

When is lividity first noticeable and when is it well-formed?

A

red patches often within 30mins (up to 2hrs)

wellformed by 4hrs

44
Q

Lividity is at its maximum intensity when?

A

8-12hrs

45
Q

Lividity that no longer blanches tells you … ?

A

Lividity is fixed after 12hrs and no longer blanches

46
Q

Which patients have minimal lividity?

A

delayed or minimal lividity in anaemia or haemorrhage

47
Q

Fixation of lividity is absolute - true or false.

A

false

fixation is when lividity no longer blanches on pressure but it is relative, not absolute.

48
Q

Primary lividity pattern fades away on moving a body and a new secondary pattern forms - how long is the PMI?

A

Movement before 6hrs (before well-formed) -> fading of primary and onset of secondary pattern

49
Q

Primary lividity remains on moving a body but a new secondary pattern still forms - how long is PMI?

A

Movement after 10hrs (well-formed but not fully fixed)
Primary pattern fixed enough to remain but enough fluid blood to form a new secondary pattern -> dual distribution e.g., front and back

50
Q

Primary lividity pattern remains on movement of body, no secondary pattern forms - how long is PMI?

A

Movement after 24hrs (well-formed and fully fixed)

Not enough fluid blood to create secondary pattern

51
Q

what does contact pallor show in relation to lividity?

A

contact pallor shows areas of pressure between lividities

52
Q

within an area of lividity there are some burst blood vessels - what is this called?

A

punctate hypostasis = burst blood vessels within congested areas of lividity

53
Q

bright pink lividity is a sign of carbon monoxide poisoning - true or false

A

FALSE
bright pink: refrigeration, hypothermia
cherry pink: CO

54
Q

chocolate brown lividity is seen in which deaths?

A

methaemoglobin (chlorate) deaths

55
Q

cyanide poisoning causes scarlet lividity - true or false

A

true

56
Q

An MI can be confused with normal lividity of the heart - true or false

A

true

the lividity of the heart mimics an MI with the posterior surface congested and the front pale

57
Q

slow initial cooling delays onset of putrefaction - true or false

A

false

slow initial cooling e.g., due to clothing or bedding will hasten putrefaction

58
Q

Describe the process of putrefaction.

A
Green discolouration in abdomen RIF 
Passage of rigor 
Marbling 
Skin blisters and slippage 
Gas production and bloating 
Loss of hair and nails, liquefaction
skeletonisation
59
Q

2 days into putrefaction process - what change is seen?

A

green discolouration starting in RIF of abdomen

60
Q

What causes the marbling sign in putrefaction?

A

blood vessels are mapped out by bacteria

61
Q

What part of putrefaction begins at 1 week?

A

gas production and bloating
methane, H2, H2S, NH3
Ptomains (putrescine, cadaverine) -> sniffer dogs!

62
Q

How long does skeletonisation take?

A

normally years

can occur in days if body is in warm environment with insects

63
Q

Which 2 organs will be softened and honeycombed by gas from internal putrefaction?

A

liver and brain are softened and honeycombed by gas

64
Q

Which organs are slow to putrefy?

A

uterus and prostate are slow to putrefy since more fibrous

65
Q

Internal putrefaction makes heart look …?

A

heart is dilated and flabby from internal putrefaction

66
Q

When can stomach contents be useful for PMI?

A

useful if time of last meal is known since food typically remains in stomach for up to 3-4hrs
NB. food can persist undigested for several day s following severe trauma (e.g. those in ITU)

67
Q

blue bottle and greenbottle flies are attracted by smell - true or false

A

true

68
Q

Which bacteria is important in the saponification process?

A

clostridium welchii

69
Q

The saponification process becomes visible after weeks/months. Where on the body might you see it?

A

cheeks, breasts, buttocks

70
Q

mummification is more common in adults vs. children - true or false

A

false
more common in infants vs. adults
partial mummification can occur in some adults during summer months (fingers and toes normally)