Pleural disease Flashcards
What are the clinical signs of pleural effusion?
- asymmetric chest expansion
- asymmetric tactile fremitus
- dullness to percussion
- absent or diminished breath sounds
What do left basal crackles indicate?
- Crackles that do not clear after a cough may indicate pulmonary edema or fluid in the alveoli due to heart failure, pulmonary fibrosis, or acute respiratory distress syndrome.
- Crackles that partially clear or change after coughing may indicate bronchiectasis.
- Crackles are often described as fine, medium, and coarse.
What does a stony dull percussion note indicate?
Fluid present in the lung
What is characteristic of pneumonia on a chest X-ray
White& fluffy indicating consolidation
What is characteristic of a pleural effusion on a chest X-ray?
- Dense white shadowing
- White shadowing creeping up the chest walls
- Hemidiaphragm not visible ( in normal x-rays, two hemidiaphragms should be visible)
What are the symptoms of pleural effusion
- chest pain.
- dry cough.
- fever.
- difficulty breathing when lying down.
- shortness of breath.
- difficulty taking deep breaths.
- persistent hiccups.
- difficulty with physical activity
Define thoracocentesis
- Removal of fluid from the space between the lungs and the chest wall (the pleural cavity) for diagnostic or therapeutic purposes using a needle inserted between the ribs.
- diagnosic procedure; light’s criteria used subsequently to determine transudate/exudate
How can we use the pleural fluid protein content to determine when a fluid is a transudate/exudate
<25g/L= transudate i.e low protein
>35g/L= exudate i.e high protein
-If 25-35g/L; use Light’s criteria
Explain the difference between a transudate and exudate
Transudate:
-Caused by systemic causes that alter the pleural equilibrium or starling forces
-fluid pushed through the capillary due to high pressure within the capillary
-Normal vessel size
-low protein present
-Fluid does not contain protein cos protein cannot pass through the small spaces between the endothelial cells
Exudate:
-Caused by inflammation
-Local causes
-Our vessel is enlarged so the gap between the endothelial cells increases, therefore allowing protein as well as fluid to escape the gap
What is Light’s criteria?
The fluid is an exudate if one/ more of the following is true:
- ) Pleural protein/serum protein >0.5
- ) Pleural LDH(lactate dehydrogenase) /serum LDH is>0.6
- ) Pleural LDH >2/3 upper limit of lab normal LDH
What are we looking for in an exudate following thoracocentesis
- Presence of protein
- Cholesterol
- Triglycerides
- Large particles
What are the causes of transudates?
Systemic causes:
- CHF
- Liver failure.cirrhosis
- Kidney failure
- Mitral stenosis
- oesophageal rupture
- Left ventricular failure
- urinothorax
- constrictive pericarditis
- Hypoalbuminaemia
- Hypothyroidism
- nephrotic syndrome
What are the causes of exudates?
Inflammatory/local causes:
- Malignancy
- Parapneumonic effusions
- TB
- Yellow nail syndrome
- PE
- Rheumatoid arthiritis
- Other autoimmune pleuritis
- Pneumonia
- Lupus
What diagnostic tests do we use to determine cause of pleural disease
- Glucose
- LDH
- pH
- MCS( multiple chemical sensitivity)
- AFB (acid fast bacteria)
- Cytology (can highlight neutropenia)
What is CRP an indication of
-inflammation/infection
What is empyema?
-A collection of pus
How can we treat empyema
-Use a chest drain e.g Saldinger chest drain
What is a parapneumonic effusion?
A parapneumonic effusion is a type of pleural effusion that arises as a result of a pneumonia, lung abscess, or bronchiectasis. There are three types of parapneumonic effusions: uncomplicated effusions, complicated effusions, and empyema.
What is a complicated parapneumonic effusion
A parapneumonic pleural effusion for which an invasive procedure, such as tube thoracostomy, is necessary for its resolution, or a parapneumonic effusion on which the bacterial cultures are positive
What is an uncomplicated parapneumonic effusion
An uncomplicated parapneumonic effusion forms when lung interstitial fluid increases during pneumonia and moves across the adjacent visceral pleural membrane. The pleural fluid is characterized by “exudative” chemistries and an influx of neutrophils into the pleural space
What is Meig’s syndrome
- Causes a transudate effusion
- The triad of benign ovarian tumor with ascites and pleural effusion that resolves after resection of the tumor. Ovarian fibromas constitute the majority of the benign tumors seen in Meigs syndrome.
What does high LDH indicate
-High levels of LDH(lactate dehydrogenase) indicate some form of tissue damage. High levels of more than one isoenzyme may indicate more than one cause of tissue damage. For example, a patient with pneumonia could also have a heart attack. Extremely high levels of LDH could indicate severe disease or multiple organ failure
What is Pleurodesis?
-A procedure that uses medicine to adhere your lung to your chest wall. It seals up the space between the outer lining of your lung& chest wall (pleural cavity) to prevent fluid or air from continually building up around your lung.
Define pnemothorax
-air present in the pleural space
shows up as black on an X-ray
