Pleural Disease Flashcards

1
Q

What are the different layers of the pleura?

A

outer - parietal
inner - visceral
in between - pleural fluid

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What are different examples of pleural problems?

A
  • pleural effusion
  • pneumothorax
  • mesothelioma
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What is a pleural effusion (PE)?

A
  • collection of fluid in the pleural space
  • imbalance between production and absorption
  • absorption: pleural lymphatics in the parietal pleura
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What are different types of effusion?

A
  • transudate: non inflammatory
  • exudate: inflammatory
  • protein content of exudate: 3g/dl or more
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What are common causes of transudates?

A
  • left ventricular failure
  • liver cirrhosis
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What are less common causes of transudates?

A
  • hypoalbuminaemia
  • peritoneal dialysis
  • hypothyroidism
  • nephrotic syndrome
  • mitral stenosis
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What are rare causes of transudates?

A
  • constrictive pericarditis
  • urinothorax
  • Meigs’ syndrome
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What are common causes of exudates?

A
  • malignancy (pulmonary and non pulmonary)
  • parapneumonic effusions, empyema
  • tuberculosis
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What are less common causes of exudates?

A
  • pulmonary embolism
  • connective tissue disease
  • benign asbestos pleural effusion
  • pancreatitis
  • post-myocardial infarction
  • post-coronary artery bypass graft
  • haemothorax, chylothorax
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What are rare causes of exudates?

A
  • yellow nail syndrome (and other lymphatic disorders e.g. lymphangioleiomyomatosis)
  • drugs
  • fungal infections
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What to do when the pH of pleural fluid is less that 7.2 along with pneumonia, pus or blood?

A

Chest drain

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What are different types of pneumothorax’s?

A
  • primary spontaneous
  • secondary spontaneous
  • traumatic
  • latrogenic
  • tension
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What are the symptoms of a tension pneumothorax?

A
  • chest pain
  • SOB
  • rapid heart rate
  • shallow breathing
  • anxiety
  • blue or ashen skin
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Where is a drain placed?

A

2nd intercostal space midclavicular line

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What are factors associated with pleural tumours?

A
  • benign: rare
  • malignant pleural effusions are common and associated with a poor outcome
  • primary malignancy: mesothelioma is the most frequent
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What is a mesothelioma?

A
  • rare, aggressive
  • caused by inhaled asbestos fibres that reach the pleura and cause inflammation which provokes tumour formation
17
Q

What are symptoms of a mesothelioma?

A
  • breathlessness
  • chest pain
  • weight loss
  • clubbed, signs of a pleural effusion
18
Q

How to diagnose a mesothelioma?

A
  • CT thorax and biopsy: needed to stage (gauge extent e.g. any distant spread etc)
  • thickened pleura
  • pleural nodules or masses
  • pleural plaques
  • an effusion
  • soft tissue infiltration
19
Q

How to manage a mesothelioma?

A
  • treatment options are limited, palliative, survival poor
  • treating the effusion
  • chemotherapy
  • recruitment to trials via MDTs
  • palliative surgery in select patients