Platelets Properties Flashcards
1
Q
Platlet Properties
A
Adhesion
Aggregation
Activation n release
2
Q
Adhesion
A
Facilit vWF
Stick to exposed collagen, non/subendothelial surfaces-vWF….via GpIb on surface of plt
3
Q
Blood disorder, memb protein deficiency
A
GpIb receptor abs-bernard soulier syndrome
vWF in plasma-vW disease
Defective platelet adhesion
4
Q
Aggregtion
A
Stick to each other
Facilit- fibrinogen, GpIIb, GpIIIa
And thrombin, adp, paf
5
Q
Secretion
A
Activation- thrombin, adp
Oval to spherical,pseudopodia-contraction of actinomycin…on activ
Plat rel, open canalic syst, granular cont, seretonin