Platelets Flashcards
Highly complex, anucleate cells that derive from bone marrow megakaryocytes.
Blood platelets
Multimeric protein synthesized by endothelial cells and megakaryocytes
Von Willebrand Factor
Offers the opportunity for evaluation of platelet numbers, size, distribution, and structure under the light microscope
Peripheral blood film
A microscopy allows more precise characterization of the structural abnormalities
Electron microscopy
Rich in glycoproteins
Glycocalyx
Submembranous band and composed of the protein tubulin provides structural support for the normally discoid cell.
Microtubules
Composed principally of actin and myosin
Microfilaments
Direct communication with the extracellular environment
Open canalicular system
Apparently derived from the smooth endoplasmic reticulum, shows positive staining for platelet peroxidase activity
Dense tubular system
calcium-sequestering pump,
Dense tubular system
