Platelets

Question 1

Megakaryocytes

Answer 1

• in red bone marrow splinter into 2000-3000 fragments to create platelets that contain many vesicles but no nucleus

Question 2

Platelets are used to

Answer 2

Clot the blood

Question 3

Under the influence of the hormone thrombopoietin, hemopoietic stem cells differentiate into

Answer 3

Platelets

Question 4

Platelets survive for

Answer 4

5-9 days

Question 5

Prp therapy

Answer 5

-procedure where blood is withdrawn and centrifuged to separate blood plasma, buffy coat(with WBC and highest concentration of platelets) and RBC
- platelet-rich blood injected back into patient at injury site to promote tissue regeneration

Question 6

Eosinophils function

Answer 6

Conlmbat effects of histamine, in allergic reactions, phagocytosis

Question 7

Neutrophils

Answer 7

Phagocytosis

Question 8

Basophils

Answer 8

Liberate heparin, histamine and serotonin in allergic reactions that intensify overall inflammatory response

Question 9

Lymphocytes

Answer 9

Mediate immune response

Question 10

Monocytes

Answer 10

Phagocytosis

Question 11

Platelets

Answer 11

Vascular spasm and blood clotting

Question 12

Hemostasis

Answer 12

Sequence of response to stop bleeding
1. Vascular spasm
2. Platelet plug formation
3. Blood clotting(coagulation)

Question 13

Blood clotting involves several (coagulation) factors. Blood clotting can be activated in one of 2 ways

Answer 13

1. Extrinsic pathway
2. Intrinsic pathway

Question 14

Extrinsic and Intrinsic pathway leads to the formation of

Answer 14

Prothrombinase, and from there the common pathway continues

Question 15

Coagulation cascade

Answer 15

1. Clotting factors cause platelets to become sticky and adhere to damaged region
   - vasoconstriction is initiated
2. Clotting factors trigger inactive prothrombin—>active thrombin
3. Thrombin catalyzes plasma protein fibrinogen(inactive)—> fibrin(active)
4. Fibrin forms a mesh of fibers around platelet plug and traps blood cells to form a temporary clot
5. When damaged region is completely repaired, the enzyme plasmid is activated to dissolve the clot

Question 16

Once the clotting forms. It

Answer 16

Retracts, tightest to pull edges of damaged vessels together

Question 17

Vitamin K is needed for

Answer 17

Normal blood clotting synthesis because it is used in the synthesis of 4 clotting factors

Question 18

Small, unwanted clots are usually dissolved by

Answer 18

Plasmin, an enzyme that is part of the fibrinolytic system