Platelet Function Test Flashcards

1
Q

Obsolete test; reflects the platelets function

A

Bleeding time

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2
Q

Provides an estimate of the integrity of the platelet plug

A

Bleeding time

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3
Q

Measures the interaction between the capillaries and platelets

A

Bleeding time

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4
Q

An infrequently performed _______ of platelet adhesion and aggregation on locally injured vascular sub endothelium

A

In vivo measurements

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5
Q

Method uses a lancet to make small, controlled puncture wound

A

Dukes Method

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6
Q

Reference interval of Dukes Method

A

2- 9 minutes

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7
Q

A blood pressure cuff is inflated at 40 mmhg

A

Standardized/ modified Ivy method

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8
Q

A calibrated spring loaded lancet is trigger on the __________ few inches distal to the ____________

A

Volar surface of forearm
Antecubital crease

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9
Q

How many incision made in standardized method

A

2

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10
Q

Reference interval for modified ivy method

A

2-9 mins

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11
Q

Degree of clot retraction is DIRECTLY PROPORTIONAL to

A

Number of platelets

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12
Q

Degree of clot retraction is INVERSELY PROPORTIONAL to

A

Hematocrit and fibrinogen

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13
Q

Evaluates how well platelets keep the clot adhered to the side of specimen tube

A

Clot retraction

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14
Q

Top tube used in clot retraction

A

Red tube (whole blood)

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15
Q

Examine clot in clot retraction in

A

1, 2, 4 and 24

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16
Q

Happens after 30 mins in clot retraction

A

Shrinks

17
Q

Remains serum after clot forms

A

40-60%

18
Q

screening test for dengue

A

capillary fragility test

19
Q

capillary fragility test is known as

A

Rumpel-Leede Capillary Fragility Test or Tourniquet Test

20
Q

A blood pressure cuff is applied and inflated to a point between the systolic and diastolic blood pressures for 5 minutes

A

capillary fragility test

21
Q

Results in Capillary Fragility Test

A

10 or more petechiae per square inch

22
Q

dengue hemorrhagic fever

A

20 or more petechiae per square inch

23
Q

Capillary Fragility test has high specificity

A

false

24
Q

confirmatory test for dengue fever

A

Ns1Ag

25
Q

size of petechiae

A

<3mm - 4mm

26
Q

size of purpura

A

3mm-1cm

27
Q

size of ecchymoses

A

> 1cm

28
Q

Adherence of platelets to glass surfaces

A

platelet adhesion

29
Q

reference value in platelet adhesion

A

> 25% retained normal
<25% retained abnormal

30
Q

platelet adhesion is a reliable method?

A

no

31
Q

method for platelet adhesiveness to glass beads (diagnosis of Von Willebrand Disease)

A

Salzmann method

32
Q

Platelet rich plasma is treated with known aggregating agents

A

Platelet aggregation

33
Q

use to measure platelet aggregation

A

spectrophotometer

34
Q

aggregating agents

A

Thrombin
Restocetin
Epinephrine
Snake Venom
Collagen
ADP

35
Q

Platelet aggregation is based on variation of

A

Born Method