Platelet Aggregometry

Question 1

Photometer used in PRP aggregometry

Answer 1

Light Transmittance aggregometer

Question 2

amount of whole blood to produce sufficient PRP

Answer 2

9-12 ml

Question 3

platelet count of PRP

Answer 3

20,000-30,000

Question 4

PRP specimen must be test within ______ to avoid __________ & loss of normal activity

Answer 4

4hrs
in vitro platelet activation

Question 5

whole blood platelet aggregometry used for measurement

Answer 5

electrical impedance

Question 6

WB platelet aggregometry specimen and storage

Answer 6

3.2% citrated plasma
15-25 degC

Question 7

ratio of normal saline and whole blood

Answer 7

1:1

Question 8

specimen is tested undiluted when

Answer 8

platelet count is less than 100,000ml

Question 9

Diagnosis of platelet dysfunction

Answer 9

PLATELET LUMIAGGREGOMETRY

Question 10

Simultaneous measurement of platelet aggregation & secretion of ATP from activated platelet dense granules.

Answer 10

PLATELET LUMIAGGREGOMETRY

Question 11

platelet agonists in aggregometry

Answer 11

Thrombin
Ristocetin
Epinephrine
Synthetic TRAP
Collagen
ADP
Arachidonic acid

Question 12

synthetic TRAP

Answer 12

Thrombin- Receptor-activating peptide

Question 13

used to check for deficiencies in the eicosanoid synthesis pathway.

Answer 13

Arachidonic acid

Question 14

used to check for abnormalities of plasma VWF in VWD

Answer 14

Ristocetin