Platelet Adhesion/Platelet Aggregation

Question 1

✓ Adherence of platelets to glass surfaces
✓ Counting the number of platelets BEFORE and AFTER exposure to glass beads.

Answer 1

Platelet Adhesion

Question 2

Not a reliable method.

Answer 2

Platelet Adhesion

Question 3

Platelet adhesiveness to glass beads (diagnosis of von Willebrand’s Disease) *not accurate

Answer 3

Salzmann Method

Question 4

Salzmann Method Normal Value:

Answer 4

> 25% of platelets adhered in the glass beads

Question 5

T/F. In Salzmann Method, if less than 25%, there’s something wrong in the quality of platelets

Answer 5

True

Question 6

T/F. In Salzmann Method, if <75% platelet retention

Answer 6

True

Question 7

Based on some variants of Born Method

Answer 7

Platelet Aggregation

Question 8

Platelet Aggregation Principle

Answer 8

Platelet rich plasma Is treated with known aggregating agents

Question 9

Cloudiness or turbidity can be measured by spectrophotometer (As aggregation proceeds, more light passes through the sample → High transmittance *directly proportional)

Answer 9

Aggregated

Question 10

Aggregating agent: (Aggregates platelets)

Answer 10

• ADP
• Collagen
• Epinephrine
• Snake Venom
• Thrombin
• Ristocetin