plasticity and functional recovery Flashcards

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1
Q

what is plasticity?

A

the ability of the brain to replace function lost by physical damage to the brain

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2
Q

what is functional recovery?

A

the ability of the brain to transfer functions from a damages area to an undamaged area

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3
Q

how does recovery work?

A

new branches of axons and dendrites must grow within neurons
(altho sometimes the brain adapts and finds another way to complete a function)

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4
Q

what are the three anatomical ways that a body can replace axon function?

A

-increased brain stimulation
-axon sprouting
-denervation supersensitivity

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5
Q

what is meant by ‘increased brain stimulation’?

A

damaged neurons effect neighbouring neurons since they no longer have an input (happens with hemispheres too)
altho damage is only on one side, the other hemisphere functions at a lower level also

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6
Q

what is meant by ‘axon sprouting’?

A

when an axon is damaged its connection with neighbouring neurons are lost
sometimes other axons that connect to that neuron will sprout extra connections, replacing the ones that were destroyed
-usually occurs 2 weeks after the damage
-only works if the damaged axon and compensatory axons do a similar job, otherwise it can cause problems

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7
Q

what is meant by ‘denervation supersensitivity’?

A

-axons that do a similar job become aroused to a higher level to compensate for the lost ones
-can have the consequence of hyper-sensitivity to messages like pain

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8
Q

what are the 4 factors affecting recovery of the brain after trauma?

A

-perseverance (sometimes lost functions may be because the individual isn’t trying)
-physical exhaustion, stress and alcohol consumption (doing a task takes much more effort)
-age (brain deteriorates when old, affects the extent and speed of recovery)
-gender (research suggests women recover better from brain injury as their function is not as lateralised)

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9
Q

Danelli et al 2013

A

-EB was operated on at 2 1/2 years old, brain tumour, most of his LH was removed, all linguistic abilities removed
-underwent intensive rehab, his language abilities started to improve at 5, continuing over the next 3 years, until there were little issues
-danelli found he had some minor grammar errors AT 17y/o
-RH had compensated but couldn’t do so entirely

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10
Q

schneider at al 2014

A

-769 people who had suffered brain injuries from road traffic incidents
-24% didn’t finish school
-51% had 12-15 years of education
-25% graduated uni
-one year after the injury, 28% had made a full recovery and were back in education/working
-39% of graduates were left free of disability
-those who left education early, only 10% made a recovery
-people who remained in education longer had greater ‘cognitive reserve’, meaning they were less likely to be left permanently disabled
-large sample shows general trends, but there are many other factors that could be involved

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11
Q

evaluate plasticity and functional recovery

A

-research has shown recovery is possible, evidence that rehabilitation programmes work
-some cases have no record of functioning prior to the damage, so its hard to know extent of recovery
-ability of the brain to recover depends on the extent of the damage, the location of it, and the person, so every case varies and generalisations are difficult

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