Plasticity And Functional Recovery Flashcards

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1
Q

Plasticity

A
  • describes the brains tendency to change and adapt as a result of experience and new learning, this generally involves a growth of new connections
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2
Q

Plasticity facts

A
  • has the ability to change throughout life
  • during infancy the brain experiences rapid growth in the number of synaptic connections it has; 15,000 per neuron at 2-3 years old (synaptic pruning)
  • twice as many in adult brain
  • as we age, rarely used connections are deleted and frequently used connections are strengthened
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3
Q

Maguire et. Al

A
  • studied the brain of london taxi drivers
  • found significantly more volume of grey matter in the posterior hippocampus than in a matched control group
  • *associated with the development of spatial and navigation skills
  • found that learning the knowledge altered the structure in taxi drivers brains, the longer they’d been in the job the more pronounced the structural difference was
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4
Q

Draganski et al

A
  • imaged the brains of medial students 3 months before and after final exams
  • learning induced changes were seen to have occurred in the hippocampus and the parietal cortex presumably as a result of the exam
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5
Q

Negative plasticity

A
  • prolonged drug use has been shown to result in poorer cognitive functioning as well as an increased dementia later in life
  • 60-80% of amputees have been known to develop phantom limb syndrome, these sensations are usually unpleasant, due to a cortical reorganisation of the somatosensory cortex as a result of the limb loss
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6
Q

Hubel and Wiesel

A
  • sewed one eye of a kitten shut and analysed the brains cortical response
  • found that the visual cortex associated with the shut eye was no idle but continued to process infomation from the open eye

-> ETHICAL ISSUES

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7
Q

Functional recovery after trauma

A
  • following damage through trauma, functional recovery is the brains ability to redistribute or transfer functions usually performed by a damaged area to other un damaged areas
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8
Q

Stage 1: axonal sprouting

A
  • growth of nerve endings which connect with other undamaged never cells to form new pathways
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9
Q

Stage 2: denervation supersensitivity

A
  • axons that do a similar job become aroused to a higher level to compensate for lost ones
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10
Q

Stage 3

A
  • recruitment of homologous areas on opposite side of the brain, damage to Broca’s area would mean the right sided equivalent would carry out function
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11
Q

Mechelli et al

A
  • compared bilingual brains to matched monolingual controls
  • found a larger parietal cortex in the brains of people who are bilingual
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