Plastic and Hand Surgery

Question 1

_______________________ is a peripheral neuropathy caused by chronic or acute compression of the median nerve under the transverse carpal ligament.

Answer 1

Carpal tunnel syndrome

Question 2

fibroproliferative disorer of the palmar fascia seen in repeat manual labor trauma and diabetics

Answer 2

dupuytren contracture (palmar fibromatosis)

Question 3

Genetic mutations associated with melanoma

Answer 3

BRAF gene mutations
V600E mutation (most common)
CDKN2A gene mutations

Question 4

The distance in millimeters between the top of the granular layer of the stratum corneum or the ulcer base of a melanoma to the deepest tumor cell. Used as aprognostic factor used in melanoma staging. Greater depth is associated with worse prognosis and higher probability of lymph node metastasis.

Answer 4

Breslow depth

Question 5

Risk factors for cutaneous squamous cell carcinoma

Answer 5

UV exposure, chronic immunosuppression, and hx of precancerious skin lesions like acitnic karatosis

Question 6

caused by genetic mutations within the sonic hedgehog signaling (SHH) pathway affecting the basal keratinocytes, hair follicles, and eccrine sweat glands

Answer 6

Basal Cell carcinoma

Question 7

A cutaneous squamous cell carcinoma that arises from chronic, nonhealing wounds (e.g., burn injuries, pressure ulcers). Typically aggressive and associated with poor prognosis due to high risk of local recurrence.

Answer 7

Marjolin ulcer

Question 8

A painless, irregularly shaped, brown-black pigmented macule involving the toe and nail bed is consistent with…..

Answer 8

acral lentiginous melanoma

Question 9

Answer 9

The photograph shows an irregularly shaped, multicolored skin lesion near the toenail that is caused by a condition most commonly seen in dark-skinned and Asian populations. Bob Marley died from this condition.

Question 10

Most common cause of gallbladder metstases

Answer 10

melanoma