plasmodium Flashcards
diseases
p.vivax,malariae,oval, falciparum
trophozoite form
active form, in RBC, ring form
erythrocytic schizont
asexual, multinucleated stage in RBC
hepatic schizont
actively divide, multinucleated, parasite in hepatocytes, no infl. resp.
merozoite
infective, break from hepatocyte/RBC, adhere and penetrate new RBC
sporozoite
mosquito salivary glands, injected into humans when bit
gametocyte
parasite gamete, from trophozoites in RBC, infective to mosquito
transmission
anopheles female mosquitoes, pregnant mother to fetus, mosquitoes bite
pathogenesis
P. Malariae - quartan malaria, 72 hrs, every 4th day
P. Vivax, Falciparum, Ovale - thirtian malaria, 48 hrs, every third day
Clinical features
abrupt onset fever, chills, headache, anemia
Life cycle - Human
- Sporozoites from mosquitoes
- Hepatic schizonts in hepatocyte
- Merozoites released into RBC
- Trophozoites formed ring shaped
- Schizont form + Merozoites
- Merozoites infect other RBC
- (sexual repr) into male and female gametes