Plasma Membrane Flashcards

1
Q

when was detailed structure of plasma membrane studied

A

only after the invention of electron microscope in 1950s

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2
Q

lipids are arranged in the plasma membrane in such a way that ____________ and ___________ heads towards the outside and ________ and ________ towards the inside
why

A

hydrophilic and polar
hydrophobic and nonpolar
so that the hydrophobic tail is protected from aqueous environment

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3
Q

in human beings, the membrane of erythrocyte has approx. _______ protein and ______ lipids

A

52 %
40%

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4
Q

depending on ___________, membrane proteins can be classified as _______ or __________

A

ease of extraction
integral
peripheral

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5
Q

location of peripheral proteins in plasma membrane

A

lie on the surface

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6
Q

location of integral proteins in plasma membrane

A

partially or totally buried in the membrane

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7
Q

integral proteins which run through the bilayer are known as

A

tunnel proteins
trans membrane proteins

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8
Q

can tunnel proteins be removed easily

A

no

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9
Q

how can tunnel proteins be removed

A

crude methods such as treatment with detergents

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10
Q

the plasma membrane has been described as

A

proteins icebergs floating in sea of phospholipids

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11
Q

improved model of structure of plasma membrane was proposed by

A

Singer and Nicolson in 1972

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12
Q

Singer and Nicolson’s model of plasma membrane was known as

A

fluid mosaic model

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13
Q

what nature of lipids allows lateral movement of proteins in the bilayer

A

quasi-fluid nature of lipids

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14
Q

fluid nature of membrane is important from the point of view of

A

cell growth
formation of intercellular junctions
secretion
endocytosis
cell division

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15
Q

passage of substanced across cell membranes occurs by methods like

A

active transport
passive transport

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16
Q

what is passive transport

A

many molecules ca move across the membrane without any requirement of energy

17
Q

_________ may move across the membrane by simple diffusion along the concentration gradient

A

neutral solutes

18
Q

what is osmosis

A

movement of water across the plasma membrane from higher to lower concentration through simple diffusion

19
Q

what is active transport

A

uphill movement where particles move against their concentration gradient

20
Q

energy for active transport if obtained from

A

ATP

21
Q

example of active transport

A

sodium or potassium pump in animal cells