Plasma Membrane Flashcards
when was detailed structure of plasma membrane studied
only after the invention of electron microscope in 1950s
lipids are arranged in the plasma membrane in such a way that ____________ and ___________ heads towards the outside and ________ and ________ towards the inside
why
hydrophilic and polar
hydrophobic and nonpolar
so that the hydrophobic tail is protected from aqueous environment
in human beings, the membrane of erythrocyte has approx. _______ protein and ______ lipids
52 %
40%
depending on ___________, membrane proteins can be classified as _______ or __________
ease of extraction
integral
peripheral
location of peripheral proteins in plasma membrane
lie on the surface
location of integral proteins in plasma membrane
partially or totally buried in the membrane
integral proteins which run through the bilayer are known as
tunnel proteins
trans membrane proteins
can tunnel proteins be removed easily
no
how can tunnel proteins be removed
crude methods such as treatment with detergents
the plasma membrane has been described as
proteins icebergs floating in sea of phospholipids
improved model of structure of plasma membrane was proposed by
Singer and Nicolson in 1972
Singer and Nicolson’s model of plasma membrane was known as
fluid mosaic model
what nature of lipids allows lateral movement of proteins in the bilayer
quasi-fluid nature of lipids
fluid nature of membrane is important from the point of view of
cell growth
formation of intercellular junctions
secretion
endocytosis
cell division
passage of substanced across cell membranes occurs by methods like
active transport
passive transport