Plaque mediated disease Flashcards

1
Q

Where can you find plaque?

A

Gingival (above the gumline), subgingival (below the gumline), smooth surface (side of tooth), approximal (inbetween teeth), fissure, crevice of gingiva

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2
Q

What is the initial phase of dental caries and is it reversible?

A

a white spot appears and yes

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3
Q

Which area of the mouth is most vulnerable?

A

molars, harder to reach

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4
Q

What are some causes of human caries?

A

eating sugar, low salivary flow, low exposure to fluoride

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5
Q

What causes dental caries?

A

bacteria are involved in the formation of lesions on the basis of their function

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6
Q

Which type of bacteria causes the most problems in terms of caries?

A

acidogenic as they can produce acid from sugar

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7
Q

Which two bacteria are best at being acidoduric and acidogenic?

A

mutans streptococci and lactobacilli

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8
Q

What does the ecological plaque hypothesis explain?

A

the polymicrobial nature of caries

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9
Q

What is disease a result of?

A

the shift in balance of the resident microflora

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10
Q

What is demineralization?

A

loss of calcium and phosphate

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11
Q

Below which pH are you at risk of caries?

A

5.5

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12
Q

How can we prevent sugars from producing cariogenic species?

A

eat less sugar

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13
Q

How can we prevent selection for cariogenic species?

A

physical removal by oral hygiene techniques such as flossing or by increasing the host’s capacity to clear the cariogenic species

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14
Q

How can we prevent low pH from increasing risk of caries?

A

fluoride exposure, enamel repair

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15
Q

How can we prevent an increase in organic acids from sugar fermentation to decrease pH?

A

buffer capacity of host saliva, some bacteria use organic acids in food chain

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16
Q

What does periodontal disease refer to?

A

disease of supporting tissues of the tooth

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17
Q

The environment of gingival crevices is aerobic. True or false?

A

False

Anaerobic

18
Q

There is lack of protein in gingival crevices. True or false?

A

False, an abundance of proteins

19
Q

Gingivitis is irreversible. True or false?

A

False, it is a reversible inflammation of the gums

20
Q

What is the fluid that surround the gingiva called?

A

Gingival curricular fluid, which is very proteinaceous in nature

21
Q

The bacteria in the gingival crevice need to be able to metabolise what?

A

Protein

22
Q

The bacteria in the gingival crevice need to be able to metabolise what?

A

True

23
Q

Is gingivitis a precursor for periodontal disease?

A

Yes

24
Q

According to the ecological plaque hypothesis, what are the characteristics of periodontal disease?

A

high subgingival biofilm levels, strong inflammatory response, high GCF flow, bleeding, high pH & temp, obligately anaerobic proteolytic biofilm

25
Q

According to the ecological plaque hypothesis, what are the characteristics of effective oral hygiene?

A

low subgingival biofilm levels, minimal inflammation, low GCF flow, presence of gram positive , facultative, saccharolytic biofilm, periodontal health

26
Q

How are periodontal diseases classified?

A

gingival diseases, chronic periodontitis, necrotising periodontal disease, aggressive periodontitis

27
Q

In chronic periodontitis, in addition to gingivitis what else occurs?

A

loss of attachment, which is irreversible, alveolar bone loss may also occur, leads to increased depth and bleeding on probing

28
Q

Why is the flora in healthy gingivae and in periodontal disease very different?

A

Some periodontopathogens can attach to the mucosa and form a biofilm coating on the tongue as there are lots of nutrients and large surface area. Thought to be a reservoir of infection

29
Q

Could tongue piercings be a risk factor for periodontal disease?

A

yes as they increase number of bacteria in the mouth

30
Q

What does necrotising mean?

A

to destroy tissue

31
Q

What are the characteristics of necrotising periodontal disease?

A

underlying systemic infection, painful, causes halitosis, grey pseudo-membrane forms on the gingivae

32
Q

What are the bacteria responsible for necrotising periodontal disease?

A

spirochaetes and fusobacteria

33
Q

Aggressive periodontitis is associated with high levels of what?

A

AA, which produces a very potent leukotoxin which destroys WBCs

34
Q

What are the characteristics of aggressive periodontitis?

A

Rare condition, usually in female teenagers, leads to a rapid loss of attachment

35
Q

How can aggressive periodontitis be treated?

A

with tetracycline/ metronidazole/ amoxicillin because of anaerobic nature of bacteria

36
Q

What is pregnancy gingivitis caused by?

A

presence of steroid hormones in GCF

37
Q

What is Group A Strep gingivitis?

A

Gingivitis caused when bacteria that causes sore throats gets into the gingival crevices

38
Q

What are the features of diabetes gingivitis?

A

inflammation, impaired healing and may increase insulin resistance

39
Q

What is HIV periodontal disease characterised by?

A

presence of opportunistic pathogens

40
Q

Is there an association between periodontal disease and general health?

A

yes, linked to CVD, respiratory disease, diabetes, risk of premature labour and risk of low birth weight

41
Q

Why does periodontal disease put you at risk of other conditions?

A

inflammation related to gram negative species results in toxic metabolites and increased LPS, the periodontium is very vascular so inflammatory mediators can reach far sites and oral bacteria can enter bloodstream