Plant Sciences Flashcards
What have plants done for us?
- food
- buildings (wood)
- materials
- clothes
- paper
- landscapes
AND MANY MORE
Global challenges
- food security and nutrition
- water security
- energy security
- medicine and pharmacology
- environmental sustainability
- wealth distribution
Norman Borlaug
Norman Borlaug won the Nobel Peace Prize 1970 for developing a semi-dwarf, high yield variety of wheat Beforehand, the wheat plants were too tall and so very fragile and subject to damage. He developed a shorter, stronger variety and so is referred to as the father of “Green revolution”
Factors challenging food security
Land and Soils
- 25% of the planet’s land is highly degraded
Climate change
- temperatures are exceeding survival thresholds of crop, tree and fish species
Energy
- modern food systems are heavily dependent on fossil fuels
- 85% of total primary energy is fossil fuel bases
World population and food security
- World population will be ~9billion by 2050
- food production will need to double
GM crops
genetically modified
Potential benefits of GM crops
- overcome linkage drag, “clean” gene movement
- introduce novel abilities
- more rapid breeding cycles
- increased food production
- improved human nutrition
- wealth distribution
- open up marginal land
- increase land and water use efficiency
- reduced environmental impact (CO2 and NO)
- reduced fertiliser use
- reduced herbicide, pesticide, fungicide, bactericide use
- reduced soil damage
Potential problems of GM crops
- commercial interests
- loss of ecological diversity
- gene transfer to wild relatives
Are GM crops unnatural?
You can also get natural genetically modified crops due to horizontal gene transfer e.g. sweet potatoes are genetically modified by agrobacterium species and are the 7th most important crop.
GM crop summary
- increases yield (22%)
- decreases pesticide quantity (-40%)
- decreases pesticide cost (39%)
- increases total production cost (3%)
- increases farmer profit (68%)
Solanum Tuberosum (GM crop)
- 3rd most important crop worldwide
- uses 2/3 water of rice for same calorific yield
- 25% of global crop lost to disease each year (enough to feed UK for 15 years!)
Phytopthora Infestans (GM crop)
- GM potato
- causative agent of the irish potato famine
- new strain “blue13” is able to overcome all current blight resistances
Challenges:
- more resistant varieties of potato
- new, less harmful control measures
In the wild, disease is the exception and resistance is the norm, so why do our potatoes get infected?
GM potato - traditional breeding vs GM
Traditional: ~25 year per gene moved
GM: ~24 months, independent of gene numbers
- transfer multiple resistance genes simultaneously
- multiple resistant potato
- yield and character maintained
Nitrogen-fixing cereals
- N2 fertiliser use accounts for 5% of global energy (and is increasing)
- N2 fertiliser allows for ~3-4x increased crop yield
- expensive
- 2/3 of applied N2 is lost to environment
Crops for the future
- snorkel rice (flood resistant)
- sub rice (submergence resistant)
- C4 rice
- golden rice - increased vitamin A content
Folk medicine
- morphine, codeine - analgaesic
- digitalin - heart arrythmia
- quinine, artemisin - malaria
- colchicine - gout
- tansy - embalming, roundworm, threadworm
- salicylic acid - warts and other skin conditions
- laudanum - pain killer and cough represent
- eating daffodils - vomiting, whooping cough, cold and asthma
Drug discovery
- 55% of drugs owe their origins to plants
- 25% of all drug are still made directly from plants
- 60% of anti-cancer drugs are of plant origin
MDR malaria
- artemisinin
- artemesia
- green small leaved plant
lung/breast/ovarian cancer
- taxol
- yew
- pine-like leaves with berries
leukaemia
- vincristine
- madagascan periwinkle
- pink/purple flowering plant with small rounded leaves
asthma
- ephedrine
- ephedra
- no leaves some small buds
pain, fever, inflammation
- asparin
- willow
chronic and acute pain
- morphine
- opium poppy
alzheimers
- galantamine
- snowdrop
bradychardia
- atropine
- deadly nightshade
- quite large pointed leaves with purple flowers
heart arrhythmia
- digoxin
- foxglove
- purple/pink cone like flowers
Metabolic diversity of plants
- high
- naturally produce anti-microbial and anti-herbivory compounds
- ~20% of all global flora re used in folk remedies
- <1% of known plant species have been assessed for bioactive compounds
Why start with natural products? (drug discovery)
- pre-screended in folk medicine (ethnopharmacology)
- active in the cell
- higher chance of biological activity
- combinatorial effecs
- community benefit
Vaccines
- 4-5 weeks after outbreak
- HIV, viral and bacterial diarrhoea, anthrax, rabies, diphtheria, malaria, alzheimer’s etc.
- can be edible
- store as seed for when needed
Plants as medical bioreactors
- many post-translational modifications are maintained, can also be “humanised”
- maintain stereochemistry
- cheap to grow
- store as seed for when needed
- edibility
- interleukin, interferon, factor VIII, hGH
Energy security
- e.g. waste miscanthus is used as straw on farms
- algae + CO2 = oil
- can use “dirty” water and waste CO2
- capture waste NPK from agricultural run off
- remove heavy metal pollutants
- algal residue contains many useful compounds
Plants as chemical bioreactors
- stereochemistry can be maintained
- complex syntheses can be achieved through gene stacking
- perform complex organic chemistry at room temperature in water
- cheap to grow
- store as seed for when needed
- main chassis for synthetic biology
Are plants conscious?
- perceive light from UV to infra-red
- detect and differentiate touch
- smell/taste more than any animal
- conduct electrical impulses and have glutamate receptors
- long and short term memory
- they are more complex at the genetic, biochemical and environmental level than any animal
What is the world’s most important food crop?
- maize (corn)
- USA is biggest producer
- staple food for the majority of the sub-saharan africa
- being used more and more for ethanol
- dometicated about 10,000 mya in southern mexico
- over 800 million metric tonnes produced
What is the second most important food crop?
- rice
- over 700 million metric tonnes produced
- main producer is China
- may be even more important than corn as a food crop as corn is used for other purposes besides consumption
- thirstiest crop (need at least 2,000 litres of water per kg)
- domesticated 11,000-12,000 mya in China
what is polished rice deficient in?
provitamin A
Which have been the focus crops of the Green revolution?
rice and wheat
Why is there pressure on food security?
the yield increases have lagged behind human population growth in areas where rice is a dominant crop for human consumption
Rice genome sequencing
- completed in Jan 2001
- could lead to breakthroughs for higher yields
Rice GM crops
- golden rice
- a cultivar that has been genetically modified to produce higher levels of vitamin A
What is the third most important crop?
- wheat
- ~700 million metric tonnes produced
- major producer is China
- covers more of earth than any other crop
- resilient, grows in dry and cold climates where rice and maize cannot
- leading source of vegetable protein for humans
- domesticated ~10,000 mya in the fertile crescent
What percentage of the world’s food energy intake do rice, maize and wheat provide?
60%
How many edible plants are there
Over 50,000
What is the fourth most important food crop?
- potatoes
- over 300 million metric tonnes produced
- China is major producer
- not a cereal like the others, the number one non-grain food product
- grows best in temperate climates
- originally grown in the Andes
- Spanish introduced to Europe in 16th century
- really high in nutrients
How much land is used for agriculture?
- half
- has a huge impact on the ecosystem and world function
- ~1/4th of that is crops
- vast majority = cereals (main three)
Where do we get the vast majority of our calories?
cereals