Plant-derived natural products approved for therapeutic use in the last thirty years (1984–2014) Flashcards

1
Q

Artemisinin

A

Malaria treatment (radical formation)

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2
Q

Arglabin

A

Cancer chemotherapy (farnesyl transferase inhibition)

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3
Q

Capsaicin

A

Postherpetic neuralgia (TRPV1 activator)

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4
Q

Colchicine

A

Gout (tubulin binding)

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5
Q

Dronabinol / Cannabidol

A

Chronic neuropathic pain (CB1 and CB2 receptor activation)

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6
Q

Galanthamine

A

Dementia associated with Alzheimer’s disease (ligand of human nicotinic acetylcholine receptors (nAChRs))

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7
Q

Ingenol mebutate

A

Actinic keratosis (inducer of cell death)

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8
Q

Masoprocol

A

Cancer chemotherapy (lipoxygenase inhibitor)

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9
Q

Omacetaxine mepesuccinate (Homoharringtonine)

A

Oncology (protein translation inhibitor)

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10
Q

Paclitaxel

A

Cancer chemotherapy (mitotic inhibitor)

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11
Q

Solamargine

A

Cancer chemotherapy (apoptosis triggering)

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