Plant-derived natural products approved for therapeutic use in the last thirty years (1984–2014) Flashcards
1
Q
Artemisinin
A
Malaria treatment (radical formation)
2
Q
Arglabin
A
Cancer chemotherapy (farnesyl transferase inhibition)
3
Q
Capsaicin
A
Postherpetic neuralgia (TRPV1 activator)
4
Q
Colchicine
A
Gout (tubulin binding)
5
Q
Dronabinol / Cannabidol
A
Chronic neuropathic pain (CB1 and CB2 receptor activation)
6
Q
Galanthamine
A
Dementia associated with Alzheimer’s disease (ligand of human nicotinic acetylcholine receptors (nAChRs))
7
Q
Ingenol mebutate
A
Actinic keratosis (inducer of cell death)
8
Q
Masoprocol
A
Cancer chemotherapy (lipoxygenase inhibitor)
9
Q
Omacetaxine mepesuccinate (Homoharringtonine)
A
Oncology (protein translation inhibitor)
10
Q
Paclitaxel
A
Cancer chemotherapy (mitotic inhibitor)
11
Q
Solamargine
A
Cancer chemotherapy (apoptosis triggering)