Plant Derivatives Flashcards
1
Q
Prevents microtuble assembly
Se: peripheral neuropathy
Cause myelosuppression
A
Vicristine
Vinblastin
2
Q
Podiphyllotoxin
Inhibits DNA topoisomerase II
tx for lung ca, NHL and GTN
A
Etoposide
3
Q
Campothecin
Inhibits TOPOisomerase I
Tx for SCLCa
A
Topotecan
4
Q
Inhibits microtubule assembly
For advanced breast and ovarian CA
A
Paclitaxel