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ANTINEOPLASTIC DRUGS > Antimetabolites > Flashcards

Antimetabolites Flashcards

1
Q

tx for lymphomas and GTN

Can cause: myelosuppression, pulmo fibrosis

A

Methotrexate

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2
Q

Rescue agent for methotrexate

A

Leucovorin (folinic acid)

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3
Q

Tx for acute leukemias
Can cause myelosuppression,
Hepatoroxicity

A

Mecaptopurine

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4
Q

Mercaptopurine metabolism is inhibited by what drug?

A

Allopurinol

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5
Q

Tx for colorectal and skin cancer

Thymine less death cells

A

5FU

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6
Q

Tx for CML in blast crisis

Most specific for S phase pf cell cycle

A

Cytarabine

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7
Q

Inhibits ribonucleotide reductase

Rx for pancreatic cancer

A

Gemcitabine

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ANTINEOPLASTIC DRUGS (5 decks)

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