Placental Hormones Flashcards

Hormone function source

1
Q

Progesterone in pregnancy secreted by

A

Cl of pregnancy till 8-10weeks

Then rest placenta

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2
Q

Cl of pregnancy is maintained by

A

Hcg

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3
Q

Life Span of cl of pregnancy

A

10-12weeks

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4
Q

Precursor of progesterone

A

Maternal LDL

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5
Q

2reactions catered by progesterone

A

Decidual reaction

Arias Stella reaction

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6
Q

Most specific hormone formed by placenta

A

Hpl

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7
Q
Hpl 
Is it protein
Secreted via /formed from
Time of release 
Aka
A

Single polypeptide
Synctitio
At 3weeks after fertilisation
Human chorionic somatotropin

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8
Q

Hcg is

How many subunit

A

Glycoprotein

Alpha and beta

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9
Q

Alpha subunit of hcg is similar to

But more similar to

A

Lh
TSH
FSH

LH diff of only 8 aa

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10
Q

Hormone with highest carbohydrate content

A

Hcg

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11
Q

Hcg is secreted by

A

Synctitio

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12
Q

Hcg is found in serum as early as

A

8 days after fertilisation / d22 / 5-6days before missed period

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13
Q

Estrogen dependent on fetus for

A

Dheas secreted by fetal adrenal gland

Which is utilised by placenta to synthesise estrogen

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14
Q

Initiation of labour is dependent on

A

Estrogen

In turn dependent on ACTH

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15
Q

If fetal adrenal gland is hypoplastic

A

Then post dated pregnancy

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16
Q

Most common estrogen during preg

Most specific during pregnancy

A

E2

E3

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17
Q

Most sensitive to detect hcg

A

FIA >RIA

18
Q

Levels of hcg max

Min

A

At 8 - 10 weeks (70)days
At 16weeks
Then remain same

19
Q

Max hcg level

A

10^ 5 iu/l

20
Q

Hcg disapperas from blood after
Normal preg
Abortion
Partial molecomplete mole

A

1-2weeks
2_4
7
9

21
Q

Hpl starts forming after

A

3 weeks of fertilisation

Then increases steadily

22
Q

Hpl max at

A

36 weeks of preg /

23
Q

Hpl production at term

A

1gm /day

24
Q

T1/2 of
Hcg
Hpl

A

24-48 hrs

10 -30 min

25
Q

Doubling time of hcg / more than / equal to 66%

A

48 hrs /

26
Q

Critical titre of hcg is min value in iul at which you can see 100,% gestational sac
TVs
Tas

A
  • 1500 iu/l

6500 iu/l />5000iu/l

27
Q

Function of hcg similar to

A

LH

28
Q

Ist stimulus to leydig to relase testosterone by

A

Hcg

29
Q

Which hornone is immunosuppressant in preg

A

Hcg

30
Q

Hcg is used in which tesr

A

Tripleand quaadraple

31
Q

Triple

A

Alpha FP

Hcg

U estriol

32
Q

Quadraple

A

Triple+ inhibin b

33
Q

Which is the connecting stalk bw placenta and fetus

A

Umbilical cord

34
Q

Normal length of uc

A

30-100cm

35
Q

Early iul how many vessels are in uc

A

4

36
Q

pH in uc

A

7.2

37
Q

Which vessel disappers later in life

A

Right umbilical vein

38
Q

What has folds of hrobokom

A

Uc

39
Q

What is Wharton’s jelly

A

Connective tissue of uc

40
Q

What is Vasa previa

A

Vilamentous attachment of cord ie if cord is attached to membranes first before placenta

41
Q

What is complication of injury in Vasa previa

A

Fetal blood loss