Placental Hormones Flashcards
Hormone function source
Progesterone in pregnancy secreted by
Cl of pregnancy till 8-10weeks
Then rest placenta
Cl of pregnancy is maintained by
Hcg
Life Span of cl of pregnancy
10-12weeks
Precursor of progesterone
Maternal LDL
2reactions catered by progesterone
Decidual reaction
Arias Stella reaction
Most specific hormone formed by placenta
Hpl
Hpl Is it protein Secreted via /formed from Time of release Aka
Single polypeptide
Synctitio
At 3weeks after fertilisation
Human chorionic somatotropin
Hcg is
How many subunit
Glycoprotein
Alpha and beta
Alpha subunit of hcg is similar to
But more similar to
Lh
TSH
FSH
LH diff of only 8 aa
Hormone with highest carbohydrate content
Hcg
Hcg is secreted by
Synctitio
Hcg is found in serum as early as
8 days after fertilisation / d22 / 5-6days before missed period
Estrogen dependent on fetus for
Dheas secreted by fetal adrenal gland
Which is utilised by placenta to synthesise estrogen
Initiation of labour is dependent on
Estrogen
In turn dependent on ACTH
If fetal adrenal gland is hypoplastic
Then post dated pregnancy
Most common estrogen during preg
Most specific during pregnancy
E2
E3
Most sensitive to detect hcg
FIA >RIA
Levels of hcg max
Min
At 8 - 10 weeks (70)days
At 16weeks
Then remain same
Max hcg level
10^ 5 iu/l
Hcg disapperas from blood after
Normal preg
Abortion
Partial molecomplete mole
1-2weeks
2_4
7
9
Hpl starts forming after
3 weeks of fertilisation
Then increases steadily
Hpl max at
36 weeks of preg /
Hpl production at term
1gm /day
T1/2 of
Hcg
Hpl
24-48 hrs
10 -30 min
