Place in Therapy

Question 1

Caramazepine

Answer 1

Partial & Generalized convulsive

Question 2

Clobazam

Answer 2

Adjunct for Lennox-Gastaut (syndrome with a mix of different seizures)

Question 3

Ethosuxamide

Answer 3

Absence ONLY

Question 4

Ezogabine

Answer 4

Adjunct for partial onset seizures in those who have failed other treatments

Question 5

Felbamate

Answer 5

Not a first line agent

Question 6

Fosphenytoin

Answer 6

Used when PO phenytoin is not feasibly or for IM/IV administration

Question 7

Gabapentin

Answer 7

Second line for partial seizures

Question 8

Lacosamide

Answer 8

Second line for partial seizures

Question 9

Lamotrigine

Answer 9

Monotherapy or adjunct for partial seizures, alternative for primary generalized seizure types and adjunct for tonic-clonic

Question 10

Levetiracetam

Answer 10

adjunct for myoclonic seizures w/ JME; adjunct for primary generalized seizures

Question 11

Oxcarbazepine

Answer 11

Monotherapy or adjunct for partial seizures; potential 1st line for primary generalized convulsive seizures

Question 12

Phenobarbital

Answer 12

Refractory seizures & neonatal.

Question 13

Phenytoin

Answer 13

First line for primary generalized convulsive and partial seizures

Question 14

Pregabalin

Answer 14

Second line for partial seizures

Question 15

Primidone

Answer 15

grandmal, psychomotor and focal seizures

Question 16

Rufinamide

Answer 16

adjunct in Lennox-Gastaut (mixed) if VPA, TOP and Lamotrigine are all failed.

Question 17

Tiagabine

Answer 17

Second line for partial seizures.

Question 18

Topiramite

Answer 18

First line for partial seizures as adjunct or primary, approved for tonic-clonic in primary generalized epilepsy

Question 19

Valproic Acid

Answer 19

First line for primary generalized seizures (myoclonic, atonic, absence), can be used for partial, useful for mixed.

Question 20

Vigabatrin

Answer 20

First line for infantile spasms, 3rd for refractory partial epilepsy.

Question 21

Zonisamide

Answer 21

Adjunct for partial seizures

Question 22

These drugs are first line/ monotherapy for partial seizures

Answer 22

Carbamazepine, lamotrigine, oxcarbazepine, phenytoin topiramate, valproic acid

Question 23

These drugs are second line/ adjunct for partial seizures

Answer 23

Ezogabine, gabapentin, lacosamide, lamotrigine, oxcarbazepine, pregablin, tiagabine, topirimate, valproic acid, vigabatrin, zonisamide

Question 24

These drugs can be used for absence seizures

Answer 24

Clobazam, ethosuxamide, lamotrigine, levetiracetam, rufinamide, topirimate, Valproic Acid,